- Concept UI
- M0082919
- Registry Numbers
- EC 1.14.14.1
- Related Numbers
- EC 1.14.13.97
- EC 1.14.14.1
- Scope Note
- A cytochrome P-450 suptype that has specificity for a broad variety of lipophilic compounds, including STEROIDS; FATTY ACIDS; and XENOBIOTICS. This enzyme has clinical significance due to its ability to metabolize a diverse array of clinically important drugs such as CYCLOSPORINE; VERAPAMIL; and MIDAZOLAM. This enzyme also catalyzes the N-demethylation of ERYTHROMYCIN.
- Terms
-
Cytochrome P-450 CYP3A
Preferred Term
Term UI
T631008
Date02/18/2005
LexicalTag
ABX
ThesaurusID
NLM (2006)
-
CYP3A
Term UI
T112919
Date01/01/1955
LexicalTag
ACR
ThesaurusID
NLM (2006)
-
Cytochrome P-450IIIA
Term UI
T112920
Date01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2006)
-
Cytochrome P450 3A
Term UI
T112921
Date01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2006)
-
Erythromycin N-Demethylase
Term UI
T112922
Date01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2006)