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Cyclosporine MeSH Descriptor Data 2022


MeSH Heading
Cyclosporine
Tree Number(s)
D04.345.566.235.300
D12.644.641.235.300
Unique ID
D016572
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016572
Annotation
a specific drug: do not confuse with CYCLOSPORINS
Scope Note
A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).
Entry Term(s)
Ciclosporin
CsA-Neoral
CyA-NOF
Cyclosporin
Cyclosporin A
Cyclosporine A
Neoral
OL 27-400
Sandimmun
Sandimmun Neoral
Sandimmune
Pharm Action
Antifungal Agents
Dermatologic Agents
Enzyme Inhibitors
Immunosuppressive Agents
Antirheumatic Agents
Calcineurin Inhibitors
Registry Number
83HN0GTJ6D
Related Numbers
59865-13-3
CAS Type 1 Name
Cyclosporin A
Previous Indexing
Cyclosporins (1982-1991)
Immunosuppressive Agents (1966-1991)
Peptides (1966-1970)
Peptides, Cyclic (1971-1981)
Public MeSH Note
1992(1982); for CYCLOSPORIN A see CYCLOSPORINS 1982-1991
History Note
1992(1982)
Entry Combination
analogs & derivatives:Cyclosporins
Date Established
1992/01/01
Date of Entry
1991/01/08
Revision Date
2019/07/01
Cyclosporine Preferred
Neoral Narrower
Sandimmun Neoral Narrower
Sandimmune Narrower
CsA-Neoral Narrower
OL 27-400 Narrower
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