MeSH Browser

MeSH Heading: Mixed Function Oxygenases
Tree Number(s): D08.811.682.690.708
Unique ID: D006899
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D006899
Annotation: do not confuse with HYDRO-LYASES
Scope Note: Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation.
Entry Term(s): Hydroxylase; Hydroxylases; Mixed Function Oxidase; Mixed Function Oxidases; Mixed Function Oxygenase; Monooxygenase; Monooxygenases
NLM Classification #: QU 140
Public MeSH Note: 2003 (1966)
History Note: 2003 (1966)
Date Established: 2003/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0010768
Scope Note: Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation.
Terms: Mixed Function Oxygenases Preferred Term
Term UI T026758
Date01/01/1984
LexicalTag NON
ThesaurusID UNK (19XX); Hydroxylases
Term UI T020778
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1966); Mixed Function Oxygenase
Term UI T000996654
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); Hydroxylase
Term UI T000996655
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); Mixed Function Oxidase
Term UI T000996656
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); Mixed Function Oxidases
Term UI T026757
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); Monooxygenase
Term UI T000996653
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); Monooxygenases
Term UI T485420
Date03/12/2002
LexicalTag NON
ThesaurusID NLM (2003)

Mixed Function Oxygenases MeSH Descriptor Data 2025