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Heme Oxygenase (Decyclizing) MeSH Descriptor Data 2025


MeSH Heading
Heme Oxygenase (Decyclizing)
Tree Number(s)
D08.811.682.690.708.410
Unique ID
D006419
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D006419
Scope Note
A mixed function oxidase enzyme which during hemoglobin catabolism catalyzes the degradation of heme to ferrous iron, carbon monoxide and biliverdin in the presence of molecular oxygen and reduced NADPH. The enzyme is induced by metals, particularly cobalt.
Entry Term(s)
Haem Oxygenase
Heme Oxygenase
Registry Numbers
EC 1.14.14.18
CAS Type 1 Name
Heme,hydrogen-donor:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)
NLM Classification #
QU 140
Previous Indexing
Heme (1966-1979)
Hydroxylases (1966-1979)
Oxygenases (1966-1979)
Public MeSH Note
98; was HEME OXYGENASE 1980-97 (see under HYDROXYLASES 1980-90)
History Note
98; was HEME OXYGENASE 1980-97 (see under HYDROXYLASES 1980-90)
Date Established
1991/01/01
Date of Entry
1979/02/21
Revision Date
2016/06/01
Heme Oxygenase (Decyclizing) Preferred
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