MeSH Browser

MeSH Heading: gamma-Butyrobetaine Dioxygenase
Tree Number(s): D08.811.682.690.708.401
Unique ID: D050563
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050563
Scope Note: An enzyme that catalyzes the HYDROXYLATION of gamma-butyrobetaine to L-CARNITINE. It is the last enzyme in the biosynthetic pathway of L-CARNITINE and is dependent on alpha-ketoglutarate; IRON; ASCORBIC ACID; and OXYGEN.
Entry Term(s): 4-Trimethylaminobutyrate, 2-Oxoglutarate Oxygen Oxidoreductase (3-Hydroxylating); Butyrobetaine Hydroxylase; Trimethylaminobutyrate Hydroxylase; gamma-Butyrobetaine Hydroxylase; gamma-Butyrobetaine, 2-Oxoglutarate Dioxygenase; gamma-Butyrobetaine,2-Oxoglutarate Dioxygenase
Registry Number: EC 1.14.11.1
Public MeSH Note: 2006; GAMMA-BUTYROBETAINE DIOXYGENASE was indexed under MIXED FUNCTION OXYGENASES 1980-2005, KETOGLUTARIC ACID 1973-1974, BETAINE 1972-1980, BUTYRATES 1974-1979, & AMINOBUTYRIC ACID 1970-1974
History Note: 2006(1980); use KETOGLUTARIC ACID 1973-1974, BETAINE 1972-1979, BUTYRATES 1974-1979, & AMINOBUTYRIC ACID 1970-1974
Date Established: 2006/01/01
Date of Entry: 2005/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

gamma-Butyrobetaine Dioxygenase MeSH Descriptor Data 2023