MeSH Browser

MeSH Heading: Kynurenine 3-Monooxygenase
Tree Number(s): D08.811.682.690.708.557
Unique ID: D050601
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050601
Scope Note: An NADPH-dependent flavin monooxygenase that plays a key role in the catabolism of TRYPTOPHAN by catalyzing the HYDROXYLATION of KYNURENINE to 3-hydroxykynurenine. It was formerly characterized as EC 1.14.1.2 and EC 1.99.1.5.
Entry Term(s): Kynurenine 3-Hydroxylase; Kynurenine Hydroxylase; L-Kynurenine-3-Hydroxylase
Registry Number: EC 1.14.13.9
Related Numbers: 9029-61-2
Public MeSH Note: 2006; KYNURENINE 3-MONOOXYGENASE was indexed under MIXED FUNCTION OXYGENASES 1981-2005, & under KYNURENINE 1973-1980
History Note: 2006(1980); KYNURENINE 1973-1979
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2013/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0076440
Registry Number: EC 1.14.13.9
Related Numbers: 9029-61-2
Scope Note: An NADPH-dependent flavin monooxygenase that plays a key role in the catabolism of TRYPTOPHAN by catalyzing the HYDROXYLATION of KYNURENINE to 3-hydroxykynurenine. It was formerly characterized as EC 1.14.1.2 and EC 1.99.1.5.
Terms: Kynurenine 3-Monooxygenase Preferred Term
Term UI T106443
LexicalTag NON
ThesaurusID NLM (2006); Kynurenine Hydroxylase
Term UI T106442
LexicalTag NON
ThesaurusID NLM (2006); Kynurenine 3-Hydroxylase
Term UI T106441
LexicalTag NON
ThesaurusID NLM (2006); L-Kynurenine-3-Hydroxylase
Term UI T620742
Date11/30/2004
LexicalTag NON
ThesaurusID NLM (2006)

Kynurenine 3-Monooxygenase MeSH Descriptor Data 2023