MeSH Browser

MeSH Heading: Pramipexole
Tree Number(s): D03.383.129.708.089.514; D03.633.100.185.514
Unique ID: D000077487
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077487
Scope Note: A benzothiazole derivative and dopamine agonist with antioxidant properties that is used in the treatment of PARKINSON DISEASE and RESTLESS LEGS SYNDROME.
Entry Term(s): 2-Amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole; 2-Amino-6-propylaminotetrahydrobenzothiazole; 4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazole-diamine; 6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine dihydrochloride monohydrate; Dexpramipexole; KNS 760704; KNS-760704; KNS760704; Mirapex; Pramipexol; Pramipexol Dihydrobromide, (+-)-isomer; Pramipexol Dihydrochloride, (S)-isomer; Pramipexol, (+-)-isomer; Pramipexol, (R)-isomer; Pramipexole Dihydrochloride; Pramipexole Dihydrochloride Anhydrous; Pramipexole Hydrochloride Monohydrate; SND 919CL2x; SND-919; SND-919CL2x; SND919CL2x; Sifrol
Pharm Action: Antioxidants
Antiparkinson Agents
Dopamine Agonists
Registry Number: 83619PEU5T
Related Numbers: 104632-25-9; 104632-26-0; 104632-28-2; 134624-04-7; 134624-05-8; 3D867NP06J; 4R2HD0M28N; WI638GUS96
CAS Type 1 Name: 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, (S)-
Public MeSH Note: 2019; PRAMIPEXOLE was indexed under BENZOTHIAZOLES 2007-2018; and under THIAZOLES 1989-2006
History Note: 2019 (1989)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/04/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, 1-Ring [D03.383]
  - Azoles [D03.383.129]
    - Thiazoles [D03.383.129.708]
      - Benzothiazoles [D03.383.129.708.089]
        
        Dithiazanine [D03.383.129.708.089.222]
        
        Ethoxzolamide [D03.383.129.708.089.416]
        
        Pramipexole [D03.383.129.708.089.514]
        
        Riluzole [D03.383.129.708.089.611]
        
        Saccharin [D03.383.129.708.089.708]

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, Fused-Ring [D03.633]
  - Heterocyclic Compounds, 2-Ring [D03.633.100]
    - Benzothiazoles [D03.633.100.185]

Pramipexole Preferred

Concept UI: M0170120
Registry Number: 83619PEU5T
Related Numbers: 104632-25-9; 104632-26-0; 104632-28-2; 134624-04-7; 134624-05-8; 3D867NP06J; 4R2HD0M28N; WI638GUS96
Scope Note: A benzothiazole derivative and dopamine agonist with antioxidant properties that is used in the treatment of PARKINSON DISEASE and RESTLESS LEGS SYNDROME.
Terms: Pramipexole Preferred Term
Term UI T000939959
Date02/01/2018
LexicalTag NON
ThesaurusID; 4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazole-diamine
Term UI T000939963
Date02/01/2018
LexicalTag NON
ThesaurusID NLM (2008); Pramipexol
Term UI T000939960
Date02/01/2018
LexicalTag NON
ThesaurusID NLM (1989); 2-Amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole
Term UI T000939962
Date02/01/2018
LexicalTag NON
ThesaurusID NLM (1989)

Dexpramipexole Narrower

Mirapex Narrower

Pramipexol Dihydrobromide, (+-)-isomer Narrower

Pramipexol Dihydrochloride, (S)-isomer Narrower

Pramipexole Dihydrochloride Anhydrous Narrower

Sifrol Narrower

SND 919CL2x Narrower

SND-919 Narrower

KNS 760704 Narrower

Pramipexol, (+-)-isomer Narrower

Pramipexole Dihydrochloride Narrower

2-Amino-6-propylaminotetrahydrobenzothiazole Related

6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine dihydrochloride monohydrate Narrower

Pramipexole MeSH Descriptor Data 2023