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Parkinson Disease MeSH Descriptor Data 2025


MeSH Heading
Parkinson Disease
Tree Number(s)
C10.228.140.079.862.500
C10.228.662.600.400
C10.574.928.750
Unique ID
D010300
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D010300
Annotation
/chem ind = PARKINSON DISEASE, SECONDARY /‌chem ind
Scope Note
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Entry Version
PARKINSON DIS
Entry Term(s)
Idiopathic Parkinson Disease
Idiopathic Parkinson's Disease
Lewy Body Parkinson Disease
Lewy Body Parkinson's Disease
Paralysis Agitans
Parkinson Disease, Idiopathic
Parkinson's Disease
Parkinson's Disease, Idiopathic
Parkinson's Disease, Lewy Body
Primary Parkinsonism
NLM Classification #
WL 359
See Also
Lewy Bodies
Public MeSH Note
1979; see PARKINSONISM 1967-1978, see PARALYSIS AGITANS 1963-1966
History Note
1979(1963)
Entry Combination
chemically induced:Parkinson Disease, Secondary /chemically induced
Date Established
1967/01/01
Date of Entry
2024/11/05
Revision Date
2024/11/05
Parkinson Disease Preferred
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