MeSH Browser

MeSH Heading: Multiple System Atrophy
Tree Number(s): C10.177.575.550; C10.228.140.079.612; C10.228.662.550; C10.574.928.625
Unique ID: D019578
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019578
Annotation: a specific neurodegenerative syndrome complex; not for atrophy in other systems
Scope Note: A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)
Entry Term(s): Multiple System Atrophy Syndrome; Multisystem Atrophy; Multisystemic Atrophy
Previous Indexing: Autonomic Nervous System Diseases (1981-1997); Brain Diseases (1981-1993); Nervous System Diseases (1969-1997); Shy-Drager Syndrome (1981-1997)
See Also: Olivopontocerebellar Atrophies; Shy-Drager Syndrome
Public MeSH Note: 1998
History Note: 1998
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2019/05/17

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0029076
Scope Note: A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)
Terms: Multiple System Atrophy Preferred Term
Term UI T058282
Date01/01/1999
LexicalTag NON
ThesaurusID; Multisystem Atrophy
Term UI T364298
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Multisystemic Atrophy
Term UI T364299
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Multiple System Atrophy Syndrome
Term UI T364305
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000)

Multiple System Atrophy MeSH Descriptor Data 2025