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Supranuclear Palsy, Progressive MeSH Descriptor Data 2025


MeSH Heading
Supranuclear Palsy, Progressive
Tree Number(s)
C10.228.140.079.882
C10.228.662.700
C10.292.562.750.500
C10.574.945.500
C10.597.622.447.690
C11.590.472.500
C23.888.592.636.447.690
Unique ID
D013494
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D013494
Scope Note
A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)
Entry Term(s)
Ophthalmoplegia, Progressive Supranuclear
Palsy, Progressive Supranuclear
Progressive Supranuclear Ophthalmoplegia
Progressive Supranuclear Palsy
Progressive Supranuclear Palsy 1
Richardson's Syndrome
Steele-Richardson-Olszewski Disease
Steele-Richardson-Olszewski Syndrome
Supranuclear Palsy, Progressive, 1
NLM Classification #
WL 358.5
Previous Indexing
Ophthalmoplegia (1979-1986)
Paralysis (1966-1986)
Paralysis, Bulbar (1966-1986)
Public MeSH Note
1987
History Note
1987
Date Established
1987/01/01
Date of Entry
1986/04/01
Revision Date
2020/02/06
Supranuclear Palsy, Progressive Preferred
Ophthalmoplegia, Progressive Supranuclear Narrower
Supranuclear Palsy, Progressive, 1 Narrower
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