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Alzheimer Disease MeSH Descriptor Data 2023


MeSH Heading
Alzheimer Disease
Tree Number(s)
C10.228.140.380.100
C10.574.945.249
F03.615.400.100
Unique ID
D000544
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000544
Scope Note
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
Entry Version
ALZHEIMER DIS
Entry Term(s)
Acute Confusional Senile Dementia
Alzheimer Dementia
Alzheimer Disease, Early Onset
Alzheimer Disease, Late Onset
Alzheimer Sclerosis
Alzheimer Syndrome
Alzheimer Type Senile Dementia
Alzheimer's Disease
Alzheimer's Disease, Focal Onset
Alzheimer's Diseases
Alzheimer-Type Dementia (ATD)
Dementia, Alzheimer Type
Dementia, Presenile
Dementia, Primary Senile Degenerative
Dementia, Senile
Early Onset Alzheimer Disease
Familial Alzheimer Disease (FAD)
Focal Onset Alzheimer's Disease
Late Onset Alzheimer Disease
Presenile Alzheimer Dementia
Primary Senile Degenerative Dementia
Senile Dementia, Acute Confusional
Senile Dementia, Alzheimer Type
See Also
Amyloid beta-Peptides
Amyloid beta-Protein Precursor
Aphasia, Primary Progressive
Cerebral Amyloid Angiopathy
Kluver-Bucy Syndrome
Neurofilament Proteins
tau Proteins
Public MeSH Note
1998; see ALZHEIMER'S DISEASE 1984-1997, see DEMENTIA, PRESENILE 1967-1983, see PSYCHOSES, PRESENILE 1963-1966; for DEMENTIA PRESENILE and DEMENTIA, PRIMARY DEGENERATIVE, SENILE see DEMENTIA 1981-1999; for DEMENTIA, SENILE see DEMENTIA 1966-1999
History Note
1998(1963); for DEMENTIA, PRESENILE and DEMENTIA, PRIMARY DEGENERATIVE SENILE use DEMENTIA 1981-1999; for DEMENTIA SENILE use DEMENTIA 1966-1999
Date Established
1984/01/01
Date of Entry
1999/01/01
Revision Date
2020/01/16
Alzheimer Disease Preferred
Acute Confusional Senile Dementia Narrower
Dementia, Presenile Narrower
Alzheimer Disease, Late Onset Narrower
Alzheimer's Disease, Focal Onset Narrower
Familial Alzheimer Disease (FAD) Narrower
Alzheimer Disease, Early Onset Narrower
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