MeSH Browser

MeSH Heading: Alzheimer Disease
Tree Number(s): C10.228.140.380.100; C10.574.945.249; F03.615.400.100
Unique ID: D000544
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000544
Scope Note: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
Entry Version: ALZHEIMER DIS
Entry Term(s): Acute Confusional Senile Dementia; Alzheimer Dementia; Alzheimer Disease, Early Onset; Alzheimer Disease, Late Onset; Alzheimer Sclerosis; Alzheimer Syndrome; Alzheimer Type Senile Dementia; Alzheimer's Disease; Alzheimer's Disease, Focal Onset; Alzheimer's Diseases; Alzheimer-Type Dementia (ATD); Dementia, Alzheimer Type; Dementia, Presenile; Dementia, Primary Senile Degenerative; Dementia, Senile; Early Onset Alzheimer Disease; Familial Alzheimer Disease (FAD); Focal Onset Alzheimer's Disease; Late Onset Alzheimer Disease; Presenile Alzheimer Dementia; Primary Senile Degenerative Dementia; Senile Dementia, Acute Confusional; Senile Dementia, Alzheimer Type
See Also: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Aphasia, Primary Progressive; Cerebral Amyloid Angiopathy; Kluver-Bucy Syndrome; Neurofilament Proteins; tau Proteins
Public MeSH Note: 1998; see ALZHEIMER'S DISEASE 1984-1997, see DEMENTIA, PRESENILE 1967-1983, see PSYCHOSES, PRESENILE 1963-1966; for DEMENTIA PRESENILE and DEMENTIA, PRIMARY DEGENERATIVE, SENILE see DEMENTIA 1981-1999; for DEMENTIA, SENILE see DEMENTIA 1966-1999
History Note: 1998(1963); for DEMENTIA, PRESENILE and DEMENTIA, PRIMARY DEGENERATIVE SENILE use DEMENTIA 1981-1999; for DEMENTIA SENILE use DEMENTIA 1966-1999
Date Established: 1984/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/01/16

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
  - Brain Diseases [C10.228.140]
    - Dementia [C10.228.140.380]

Nervous System Diseases [C10]
- Neurodegenerative Diseases [C10.574]
  - Tauopathies [C10.574.945]

Mental Disorders [F03]
- Neurocognitive Disorders [F03.615]
  - Dementia [F03.615.400]

Alzheimer Disease Preferred

Concept UI: M0000842
Scope Note: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
Terms: Alzheimer Disease Preferred Term
Term UI T001655
Date01/01/1999
LexicalTag EPO
ThesaurusID; Alzheimer Syndrome
Term UI T840888
Date04/18/2013
LexicalTag NON
ThesaurusID GHR (2014); Alzheimer-Type Dementia (ATD)
Term UI T843727
Date05/07/2013
LexicalTag NON
ThesaurusID GHR (2014); Alzheimer's Diseases
Term UI T000998303
Date11/20/2019
LexicalTag EPO
ThesaurusID NLM (2021); Alzheimer Dementia
Term UI T000915952
Date02/17/2017
LexicalTag NON
ThesaurusID; Alzheimer's Disease
Term UI T001654
Date09/16/1996
LexicalTag EPO
ThesaurusID; Dementia, Senile
Term UI T010820
Date05/23/1997
LexicalTag NON
ThesaurusID NLM (1966); Dementia, Alzheimer Type
Term UI T365964
Date11/08/1999
LexicalTag EPO
ThesaurusID NLM (2000); Senile Dementia, Alzheimer Type
Term UI T365965
Date11/08/1999
LexicalTag EPO
ThesaurusID NLM (2000); Alzheimer Type Senile Dementia
Term UI T365981
Date11/08/1999
LexicalTag EPO
ThesaurusID NLM (2000); Primary Senile Degenerative Dementia
Term UI T366224
Date11/08/1999
LexicalTag NON
ThesaurusID; Alzheimer Sclerosis
Term UI T840887
Date04/18/2013
LexicalTag NON
ThesaurusID GHR (2014); Dementia, Primary Senile Degenerative
Term UI T369933
Date11/08/1999
LexicalTag NON
ThesaurusID NLM (2000)

Dementia, Presenile Narrower

Acute Confusional Senile Dementia Narrower

Alzheimer Disease, Early Onset Narrower

Alzheimer Disease, Late Onset Narrower

Alzheimer's Disease, Focal Onset Narrower

Familial Alzheimer Disease (FAD) Narrower

Alzheimer Disease MeSH Descriptor Data 2025