MeSH Browser

MeSH Heading: Aphasia, Primary Progressive
Tree Number(s): C10.228.140.380.132; C10.597.606.150.500.800.100.155; C23.888.592.604.150.500.800.100.155; F03.615.400.125
Unique ID: D018888
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018888
Annotation: a clinical entity: do not confuse with descriptions of the progression of aphasia in case reports
Scope Note: A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE, emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26)
Entry Term(s): Mesulam Syndrome; Mesulam's Syndrome
Previous Indexing: Aphasia (1982-1995)
Public MeSH Note: 1996
History Note: 1996
Date Established: 1996/01/01
Date of Entry: 1994/12/27
Revision Date: 2015/06/30

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

virology (VI)

Concept UI: M0028247
Scope Note: A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE, emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26)
Terms: Aphasia, Primary Progressive Preferred Term
Term UI T056302
Date01/01/1999
LexicalTag NON
ThesaurusID; Mesulam's Syndrome
Term UI T056300
Date08/26/1994
LexicalTag EPO
ThesaurusID NLM (1996); Mesulam Syndrome
Term UI T056301
Date08/26/1994
LexicalTag EPO
ThesaurusID NLM (1996)

Aphasia, Primary Progressive MeSH Descriptor Data 2025