MeSH Browser

MeSH Heading: Pick Disease of the Brain
Tree Number(s): C10.228.140.380.266.299.500; F03.615.400.380.299.500
Unique ID: D020774
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020774
Scope Note: A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9)
Entry Version: PICK DIS OF THE BRAIN
Entry Term(s): Brain Atrophy, Circumscribed Lobar; Circumscribed Lobar Atrophy of the Brain; Dementia with Lobar Atrophy and Neuronal Cytoplasmic Inclusions; Lobar Atrophy (Brain); Lobar Atrophy Of Brain; Lobar Atrophy of the Brain; Pick Disease; Pick Disease Of Brain; Pick's Disease; Picks Disease of Brain
Previous Indexing: Dementia (1966-1999)
Public MeSH Note: 2000; for PICKS DISEASE OF BRAIN see DEMENTIA 1992-1999
History Note: 2000; for PICKS DISEASE OF BRAIN use DEMENTIA 1992-1999
Date Established: 2000/01/01
Date of Entry: 1999/11/05
Revision Date: 2015/06/23

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

virology (VI)

Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
  - Brain Diseases [C10.228.140]
    - Dementia [C10.228.140.380]
      - Frontotemporal Lobar Degeneration [C10.228.140.380.266]
        
        Frontotemporal Dementia [C10.228.140.380.266.299]
        
        Pick Disease of the Brain [C10.228.140.380.266.299.500]

Mental Disorders [F03]
- Neurocognitive Disorders [F03.615]
  - Dementia [F03.615.400]
    - Frontotemporal Lobar Degeneration [F03.615.400.380]
      - Frontotemporal Dementia [F03.615.400.380.299]
        
        Pick Disease of the Brain [F03.615.400.380.299.500]

Pick Disease of the Brain Preferred

Concept UI: M0005800
Scope Note: A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9)
Terms: Pick Disease of the Brain Preferred Term
Term UI T010821
Date06/18/1997
LexicalTag EPO
ThesaurusID; Brain Atrophy, Circumscribed Lobar
Term UI T369919
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Pick Disease
Term UI T369920
Date10/12/1999
LexicalTag EPO
ThesaurusID NLM (2000); Picks Disease of Brain
Term UI T010822
Date03/18/1997
LexicalTag EPO
ThesaurusID NLM (1992); Circumscribed Lobar Atrophy of the Brain
Term UI T369917
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Pick's Disease
Term UI T369921
Date10/12/1999
LexicalTag EPO
ThesaurusID; Lobar Atrophy of the Brain
Term UI T750418
Date05/04/2009
LexicalTag NON
ThesaurusID; Dementia with Lobar Atrophy and Neuronal Cytoplasmic Inclusions
Term UI T781527
Date12/02/2010
LexicalTag NON
ThesaurusID; Pick Disease Of Brain
Term UI T812127
Date11/15/2011
LexicalTag NON
ThesaurusID OMIM (2013); Lobar Atrophy (Brain)
Term UI T369918
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Lobar Atrophy Of Brain
Term UI T812128
Date11/15/2011
LexicalTag NON
ThesaurusID OMIM (2013)

Pick Disease of the Brain MeSH Descriptor Data 2025