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Hot Melt Extrusion Technology MeSH Descriptor Data 2025


MeSH Heading
Hot Melt Extrusion Technology
Tree Number(s)
E05.916.840
J01.897.360.500
J01.897.836.500
Unique ID
D000080048
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000080048
Scope Note
Solvent-free method for preparing numerous types of drug delivery systems and dosage forms for active pharmaceutical ingredients that have solubility issues. It involves pumping polymeric materials at temperatures above their glass transition temperature to mix in active pharmaceutical ingredients with or without binders thus forming an amorphous product with an increase in the dissolution profile for the active pharmaceutical ingredients.
Entry Term(s)
Hot Melt Extrusion
Public MeSH Note
2020
History Note
2020
Date Established
2020/01/01
Date of Entry
2019/07/08
Revision Date
2019/05/30
Hot Melt Extrusion Technology Preferred
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