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Macroautophagy
MeSH Descriptor Data 2024
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Macroautophagy
Tree Number(s)
G04.011.750
Unique ID
D000080550
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000080550
Scope Note
The segregation of large parts of the cytoplasm, including
ORGANELLES
and
PROTEIN AGGREGATES
, into
AUTOPHAGOSOMES
and lysosomal degradation after fusion with
LYSOSOMES
.
Entry Term(s)
Aggrephagy
Chaperone-Assisted-Selective Autophagy
Lysophagy
Macro-Autophagy
Pexophagy
Proteaphagy
Xenophagy
Previous Indexing
Autophagy (1991-2019)
Public MeSH Note
2020; see AUTOPHAGY 2017-2019
History Note
2020; use AUTOPHAGY 2017-2019
Date Established
2020/01/01
Date of Entry
2019/07/08
Revision Date
2019/07/05
Allowable Qualifiers
drug effects (DE)
genetics (GE)
immunology (IM)
physiology (PH)
radiation effects (RE)
Cell Physiological Phenomena [G04]
Autophagy [G04.011]
Autophagic Cell Death [G04.011.500]
Chaperone-Mediated Autophagy [G04.011.625]
Efferocytosis [G04.011.688]
Macroautophagy [G04.011.750]
Microautophagy [G04.011.875]
Mitophagy [G04.011.937]
Expand All
Collapse All
Macroautophagy
Preferred
Concept UI
M000647960
Scope Note
The segregation of large parts of the cytoplasm, including
ORGANELLES
and
PROTEIN AGGREGATES
, into
AUTOPHAGOSOMES
and lysosomal degradation after fusion with
LYSOSOMES
.
Terms
Macroautophagy
Preferred Term
Term UI
T000893469
Date
01/11/2016
LexicalTag
NON
ThesaurusID
NLM (2017)
Macro-Autophagy
Term UI
T000954101
Date
03/28/2019
LexicalTag
NON
ThesaurusID
NLM (2020)
Pexophagy
Narrower
Concept UI
M000648265
Scope Note
Macroautophagic degradation of
PEROXISOMES
. In yeast peroxisomes are degraded via a microautophagic process known as
MICROPEXOPHAGY
.
Terms
Pexophagy
Preferred Term
Term UI
T000954097
Date
03/28/2019
LexicalTag
NON
ThesaurusID
NLM (2020)
Xenophagy
Narrower
Concept UI
M000648266
Scope Note
Autophagic degradation of microorganisms in the
CYTOPLASM
.
Terms
Xenophagy
Preferred Term
Term UI
T000954098
Date
03/28/2019
LexicalTag
NON
ThesaurusID
NLM (2020)
Proteaphagy
Narrower
Concept UI
M000648267
Scope Note
Macroautophagic degradation of PROTEASOMES.
Terms
Proteaphagy
Preferred Term
Term UI
T000954099
Date
03/28/2019
LexicalTag
NON
ThesaurusID
NLM (2020)
Lysophagy
Narrower
Concept UI
M000648268
Scope Note
Autophagic degradation of damaged
LYSOSOMES
.
Terms
Lysophagy
Preferred Term
Term UI
T000954100
Date
03/28/2019
LexicalTag
NON
ThesaurusID
NLM (2020)
Aggrephagy
Narrower
Concept UI
M000648270
Terms
Aggrephagy
Preferred Term
Term UI
T000954103
Date
03/28/2019
LexicalTag
NON
ThesaurusID
NLM (2020)
Chaperone-Assisted-Selective Autophagy
Broader
Concept UI
M000648271
Scope Note
A selective type of macroautophagy in which
PROTEIN AGGREGATES
that are bound to chaperone HSPPA8 and other co-chaperones are taken in for lysosomal degradation by invagination. It is distinguished from
CHAPERONE-MEDIATED AUTOPHAGY
.
Terms
Chaperone-Assisted-Selective Autophagy
Preferred Term
Term UI
T000954104
Date
03/28/2019
LexicalTag
NON
ThesaurusID
NLM (2020)
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