R-Loop Structures MeSH Descriptor Data 2025

MeSH Heading: R-Loop Structures
Tree Number(s): G02.111.570.820.486.690; G05.360.580.690
Unique ID: D000080870
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000080870
Scope Note: An RNA-DNA hybrid structure formed when newly transcribed RNA remains bound to its DNA template. Stability of R-loops may play a role in GENETIC INSTABILITY.
Entry Term(s): R-Loop; R-Loops
Public MeSH Note: 2020
History Note: 2020
Date Established: 2020/01/01
Date of Entry: 2019/07/08
Revision Date: 2020/05/27

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Chemical Phenomena [G02]
- Biochemical Phenomena [G02.111]
  - Molecular Structure [G02.111.570]
    - Molecular Conformation [G02.111.570.820]
      - Nucleic Acid Conformation [G02.111.570.820.486]
        
        Base Pairing [G02.111.570.820.486.100]
        
        DNA, A-Form [G02.111.570.820.486.128]
        
        DNA, B-Form [G02.111.570.820.486.142]
        
        DNA, C-Form [G02.111.570.820.486.156]
        
        DNA, Circular [G02.111.570.820.486.212]
        
        DNA, Concatenated [G02.111.570.820.486.268]
        
        DNA, Cruciform [G02.111.570.820.486.325]
        
        DNA, Single-Stranded [G02.111.570.820.486.437]
        
        DNA, Z-Form [G02.111.570.820.486.493]
        
        G-Quadruplexes [G02.111.570.820.486.550]
        
        Nucleotide Motifs [G02.111.570.820.486.662]
        
        R-Loop Structures [G02.111.570.820.486.690]
        
        RNA Folding [G02.111.570.820.486.718]
        
        RNA, Double-Stranded [G02.111.570.820.486.775]
        
        RNA, Z-Form [G02.111.570.820.486.776]

Genetic Phenomena [G05]
- Genetic Structures [G05.360]
  - Nucleic Acid Conformation [G05.360.580]

R-Loop Structures Preferred

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