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G-Quadruplexes MeSH Descriptor Data 2025


MeSH Heading
G-Quadruplexes
Tree Number(s)
G02.111.570.820.486.550
G05.360.580.550
Unique ID
D054856
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D054856
Scope Note
Higher-order DNA and RNA structures formed from guanine-rich sequences. They are formed around a core of at least 2 stacked tetrads of hydrogen-bonded GUANINE bases. They can be formed from one two or four separate strands of DNA (or RNA) and can display a wide variety of topologies, which are a consequence of various combinations of strand direction, length, and sequence. (From Nucleic Acids Res. 2006;34(19):5402-15)
Entry Term(s)
DNA G-Quadruplexes
DNA, Quadruplex
G-Quadruplexes, DNA
G-Quadruplexes, RNA
Guanine-Quadruplexes
Guanine-Quartets
Guanine-Tetrads
Quadruplex DNA
RNA, G-Quadruplexes
Tetraplex DNA
See Also
DNA, Cruciform
Public MeSH Note
2008; QUADRAPLEX DNA was indexed under DNA 1994-2007
History Note
2008 (1994)
Date Established
2008/01/01
Date of Entry
2007/07/09
Revision Date
2015/06/22
G-Quadruplexes Preferred
G-Quadruplexes, DNA Narrower
G-Quadruplexes, RNA Narrower
Guanine-Tetrads Related
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