Single-Case Studies as Topic MeSH Descriptor Data 2025

MeSH Heading: Single-Case Studies as Topic
Tree Number(s): E05.318.372.250.250.682; N05.715.360.330.250.250.682; N06.850.520.450.250.250.682
Unique ID: D000080907
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000080907
Scope Note: Trials that consider an individual patient as the sole unit of observation in a study investigating the efficacy or side-effects of different interventions to determine the optimal intervention for an individual patient using objective data-driven criteria.
Entry Term(s): N-of-1 Trials as Topic; Single-Case Study; Single-Case Trial; Single-Subject Trial
Previous Indexing: Clinical Trials as Topic (2010-2019)
Public MeSH Note: 2020
History Note: 2020
Date Established: 2020/01/01
Date of Entry: 2019/07/08
Revision Date: 2019/07/07

Allowable Qualifiers: classification (CL)

economics (EC)

ethics (ES)

history (HI)

instrumentation (IS)

legislation & jurisprudence (LJ)

methods (MT)

organization & administration (OG)

psychology (PX)

statistics & numerical data (SN)

Investigative Techniques [E05]
- Epidemiologic Methods [E05.318]
  - Epidemiologic Study Characteristics [E05.318.372]
    - Clinical Studies as Topic [E05.318.372.250]
      - Clinical Trials as Topic [E05.318.372.250.250]
        
        Adaptive Clinical Trials as Topic [E05.318.372.250.250.100]
        
        Clinical Trials, Phase I as Topic [E05.318.372.250.250.200]
        
        Clinical Trials, Phase II as Topic [E05.318.372.250.250.210]
        
        Clinical Trials, Phase III as Topic [E05.318.372.250.250.220]
        
        Clinical Trials, Phase IV as Topic [E05.318.372.250.250.230]
        
        Controlled Clinical Trials as Topic [E05.318.372.250.250.365]
        
        Human Challenge Trials as Topic [E05.318.372.250.250.524]
        
        Single-Case Studies as Topic [E05.318.372.250.250.682]

Health Care Quality, Access, and Evaluation [N05]
- Quality of Health Care [N05.715]
  - Health Care Evaluation Mechanisms [N05.715.360]
    - Epidemiologic Study Characteristics [N05.715.360.330]
      - Clinical Studies as Topic [N05.715.360.330.250]
        
        Clinical Trials as Topic [N05.715.360.330.250.250]
        
        Adaptive Clinical Trials as Topic [N05.715.360.330.250.250.100]
        
        Clinical Trials, Phase I as Topic [N05.715.360.330.250.250.200]
        
        Clinical Trials, Phase II as Topic [N05.715.360.330.250.250.210]
        
        Clinical Trials, Phase III as Topic [N05.715.360.330.250.250.220]
        
        Clinical Trials, Phase IV as Topic [N05.715.360.330.250.250.230]
        
        Controlled Clinical Trials as Topic [N05.715.360.330.250.250.365]
        
        Human Challenge Trials as Topic [N05.715.360.330.250.250.524]
        
        Single-Case Studies as Topic [N05.715.360.330.250.250.682]

Environment and Public Health [N06]
- Public Health [N06.850]
  - Epidemiologic Methods [N06.850.520]
    - Epidemiologic Study Characteristics [N06.850.520.450]
      - Clinical Studies as Topic [N06.850.520.450.250]
        
        Clinical Trials as Topic [N06.850.520.450.250.250]
        
        Adaptive Clinical Trials as Topic [N06.850.520.450.250.250.100]
        
        Clinical Trials, Phase I as Topic [N06.850.520.450.250.250.200]
        
        Clinical Trials, Phase II as Topic [N06.850.520.450.250.250.210]
        
        Clinical Trials, Phase III as Topic [N06.850.520.450.250.250.220]
        
        Clinical Trials, Phase IV as Topic [N06.850.520.450.250.250.230]
        
        Controlled Clinical Trials as Topic [N06.850.520.450.250.250.365]
        
        Human Challenge Trials as Topic [N06.850.520.450.250.250.524]
        
        Single-Case Studies as Topic [N06.850.520.450.250.250.682]

Single-Case Studies as Topic Preferred

Concept UI: M000648724
Scope Note: Trials that consider an individual patient as the sole unit of observation in a study investigating the efficacy or side-effects of different interventions to determine the optimal intervention for an individual patient using objective data-driven criteria.
Terms: Single-Case Studies as Topic Preferred Term
Term UI T000955756
Date04/17/2019
LexicalTag NON
ThesaurusID NLM (2020); Single-Case Study
Term UI T000955752
Date04/17/2019
LexicalTag NON
ThesaurusID NLM (2020); Single-Case Trial
Term UI T000955753
Date04/17/2019
LexicalTag NON
ThesaurusID NLM (2020); Single-Subject Trial
Term UI T000955754
Date04/17/2019
LexicalTag NON
ThesaurusID NLM (2020); N-of-1 Trials as Topic
Term UI T000955755
Date04/17/2019
LexicalTag NON
ThesaurusID NLM (2020)

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