MeSH Browser

MeSH Heading: Promyelocytic Leukemia Nuclear Bodies
Tree Number(s): A11.284.430.106.279.345.574.875
Unique ID: D000088182
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000088182
Scope Note: Spherical intranuclear membraneless bodies nucleated by PROMYELOCYTIC LEUKEMIA PROTEIN and various other proteins containing small ubiquitin-related modifier (SUMO) interaction motif (SIM) and/or sumoylated proteins (e.g., Sp100 protein). Promyelocytic leukemia nuclear bodies regulate posttranslational modifications of partner proteins (e.g., SUMOYLATION) which in turn lead to modulation of various biological processes.
Entry Term(s): PML Bodies; PML NBs; PML Nuclear Bodies; Promyelocytic Leukemia Nuclear Body; Promyelocytic Leukemia Protein Bodies; Promyelocytic Leukemia Protein Body
Previous Indexing: Intranuclear Inclusion Bodies (2008-2021); Promyelocytic Leukemia Protein (2008-2021)
Public MeSH Note: 2022
History Note: 2022
Date Established: 2022/01/01
Date of Entry: 2021/07/09
Revision Date: 2021/07/01

Allowable Qualifiers: chemistry (CH)

classification (CL)

drug effects (DE)

enzymology (EN)

genetics (GE)

immunology (IM)

metabolism (ME)

microbiology (MI)

parasitology (PS)

pathology (PA)

physiology (PH)

radiation effects (RE)

transplantation (TR)

ultrastructure (UL)

virology (VI)

Concept UI: M000740236
Scope Note: Spherical intranuclear membraneless bodies nucleated by PROMYELOCYTIC LEUKEMIA PROTEIN and various other proteins containing small ubiquitin-related modifier (SUMO) interaction motif (SIM) and/or sumoylated proteins (e.g., Sp100 protein). Promyelocytic leukemia nuclear bodies regulate posttranslational modifications of partner proteins (e.g., SUMOYLATION) which in turn lead to modulation of various biological processes.
Terms: Promyelocytic Leukemia Nuclear Bodies Preferred Term
Term UI T001092291
Date11/24/2020
LexicalTag NON
ThesaurusID NLM (2022); Promyelocytic Leukemia Nuclear Body
Term UI T001092292
Date11/24/2020
LexicalTag NON
ThesaurusID NLM (2022); Promyelocytic Leukemia Protein Bodies
Term UI T001092285
Date11/24/2020
LexicalTag NON
ThesaurusID NLM (2022); PML Nuclear Bodies
Term UI T001092290
Date11/24/2020
LexicalTag ABX
ThesaurusID NLM (2022); Promyelocytic Leukemia Protein Body
Term UI T001092293
Date11/24/2020
LexicalTag NON
ThesaurusID NLM (2022); PML Bodies
Term UI T001092289
Date11/24/2020
LexicalTag ABX
ThesaurusID NLM (2022); PML NBs
Term UI T001092304
Date11/24/2020
LexicalTag ABB
ThesaurusID NLM (2022)

Promyelocytic Leukemia Nuclear Bodies MeSH Descriptor Data 2025