A subset of activated B cells generated in response to primary immune challenge or immunization which are capable of giving rise to antibody-secreting cells upon re-challenge (see IMMUNOLOGIC MEMORY). Memory B cells feature many discrete properties indicative of differentiation through ISOTYPE SWITCHING and/or IMMUNOGLOBULIN SOMATIC HYPERMUTATION for rapid and robust recall of specific antibody responses.
A subset of activated B cells generated in response to primary immune challenge or immunization which are capable of giving rise to antibody-secreting cells upon re-challenge (see IMMUNOLOGIC MEMORY). Memory B cells feature many discrete properties indicative of differentiation through ISOTYPE SWITCHING and/or IMMUNOGLOBULIN SOMATIC HYPERMUTATION for rapid and robust recall of specific antibody responses.
