MeSH Browser

MeSH Heading: Microphysiological Systems
Tree Number(s): A10.802.500; E01.370.225.500.223.250.500; E05.200.500.265.125.500; E05.242.223.375.500; E05.481.500.249.312.500; E07.305.343.500.500
Unique ID: D000094182
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000094182
Scope Note: Devices designed to recapitulate tissue or organ-level physiology and architect by combining MICROFLUIDICS; MICROFABRICATION; and 3D CELL CULTURE. Microphysiological systems mimic interconnections important in physiological or pathophysiological states of organ(s) and are often used for instance in HIGH THROUGHPUT SCREENING of drugs and factors important in disease modeling.
Entry Term(s): Organ Chips; Organ-on-Chip Microfluidic Devices; Organ-on-a-Chip; Organ-on-a-Chip Devices; Organoids-on-a-Chip; Organotypic Cell Cultures; Organotypic Cultures; Organotypic Models; Organs on Chips
Previous Indexing: Lab-On-A-Chip Devices (2014-2022)
See Also: Tissue Engineering
Public MeSH Note: 2023
History Note: 2023
Date Established: 2023/01/01
Date of Entry: 2022/07/08
Revision Date: 2023/06/01

Allowable Qualifiers: adverse effects (AE)

classification (CL)

economics (EC)

ethics (ES)

history (HI)

microbiology (MI)

parasitology (PS)

standards (ST)

statistics & numerical data (SN)

supply & distribution (SD)

trends (TD)

veterinary (VE)

virology (VI)

Tissues [A10]
- Organoids [A10.802]
  - Microphysiological Systems [A10.802.500]

Diagnosis [E01]
- Diagnostic Techniques and Procedures [E01.370]
  - Clinical Laboratory Techniques [E01.370.225]
    - Cytological Techniques [E01.370.225.500]
      - Cell Culture Techniques [E01.370.225.500.223]
        
        Cell Culture Techniques, Three Dimensional [E01.370.225.500.223.250]
        
        Microphysiological Systems [E01.370.225.500.223.250.500]

Investigative Techniques [E05]
- Clinical Laboratory Techniques [E05.200]
  - Cytological Techniques [E05.200.500]
    - Cell Culture Techniques [E05.200.500.265]
      - Cell Culture Techniques, Three Dimensional [E05.200.500.265.125]
        
        Microphysiological Systems [E05.200.500.265.125.500]

Investigative Techniques [E05]
- Cytological Techniques [E05.242]
  - Cell Culture Techniques [E05.242.223]
    - Cell Culture Techniques, Three Dimensional [E05.242.223.375]
      - Microphysiological Systems [E05.242.223.375.500]

Investigative Techniques [E05]
- In Vitro Techniques [E05.481]
  - Culture Techniques [E05.481.500]
    - Cell Culture Techniques [E05.481.500.249]
      - Cell Culture Techniques, Three Dimensional [E05.481.500.249.312]
        
        Microphysiological Systems [E05.481.500.249.312.500]

Equipment and Supplies [E07]
- Electrical Equipment and Supplies [E07.305]
  - Micro-Electrical-Mechanical Systems [E07.305.343]
    - Lab-On-A-Chip Devices [E07.305.343.500]
      - Microphysiological Systems [E07.305.343.500.500]

Microphysiological Systems Preferred

Concept UI: M000755665
Scope Note: Devices designed to recapitulate tissue or organ-level physiology and architect by combining MICROFLUIDICS; MICROFABRICATION; and 3D CELL CULTURE. Microphysiological systems mimic interconnections important in physiological or pathophysiological states of organ(s) and are often used for instance in HIGH THROUGHPUT SCREENING of drugs and factors important in disease modeling.
Terms: Microphysiological Systems Preferred Term
Term UI T001118765
Date03/14/2022
LexicalTag NON
ThesaurusID NLM (2023); Organs on Chips
Term UI T001123485
Date08/15/2022
LexicalTag NON
ThesaurusID NLM (2024); Organotypic Models
Term UI T001120185
Date05/02/2022
LexicalTag NON
ThesaurusID NLM (2023); Organ-on-a-Chip Devices
Term UI T001118766
Date03/14/2022
LexicalTag NON
ThesaurusID NLM (2023); Organoids-on-a-Chip
Term UI T001118767
Date03/14/2022
LexicalTag NON
ThesaurusID NLM (2023); Organ Chips
Term UI T001118768
Date03/14/2022
LexicalTag NON
ThesaurusID NLM (2023); Organ-on-a-Chip
Term UI T001118769
Date03/14/2022
LexicalTag NON
ThesaurusID NLM (2023); Organotypic Cultures
Term UI T001120187
Date05/02/2022
LexicalTag NON
ThesaurusID NLM (2023); Organotypic Cell Cultures
Term UI T001120188
Date05/02/2022
LexicalTag NON
ThesaurusID NLM (2023); Organ-on-Chip Microfluidic Devices
Term UI T001123484
Date08/15/2022
LexicalTag NON
ThesaurusID NLM (2024)

Microphysiological Systems MeSH Descriptor Data 2025