MeSH Browser

MeSH Heading: Sphingosine Kinase
Tree Number(s): D08.811.913.696.620.723
Unique ID: D000099157
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000099157
Scope Note: The catalyst to phosphorylate SPHINGOSINE into sphingosine-1-phosphate; Important in ANGIOGENESIS, CELL SURVIVAL, and CELL MIGRATION
Entry Term(s): SPHK1 Enzyme; Sphingosine Kinase Type 1; Sphingosine Kinase Type 2; Sphingosine Kinase-1; Sphingosine Kinase-2
Registry Numbers: EC 2.7.1.91; EC 2.7.1.91; EC 2.7.1.91
Public MeSH Note: 2026; SPHINGOSINE KINASE was indexed under PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR) 1993-2025 and under PHOSPHOTRANSFERASES, ATP 1975-1993 and under SPHINGOSINE 1975-1982
History Note: 2026 (1975)
Date Introduced: 2026/01/01
Last Updated: 2026/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Sphingosine Kinase MeSH Descriptor Data 2026