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Adie Syndrome MeSH Descriptor Data 2025


MeSH Heading
Adie Syndrome
Tree Number(s)
C10.177.045
C10.292.562.700.250
C11.590.436.200
C11.710.800.180
Unique ID
D000270
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000270
Scope Note
A syndrome characterized by a TONIC PUPIL that occurs in combination with decreased lower extremity reflexes. The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction. Pathologic features include degeneration of the ciliary ganglion and postganglionic parasympathetic fibers that innervate the pupillary constrictor muscle. (From Adams et al., Principles of Neurology, 6th ed, p279)
Entry Term(s)
Adie's Syndrome
Holmes-Adie Syndrome
Poorly Reacting Pupils
Public MeSH Note
2000; see ADIE'S SYNDROME 1963-1999
History Note
2000 (1963)
Date Established
2000/01/01
Date of Entry
1999/01/01
Revision Date
2022/04/19
Adie Syndrome Preferred
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