MeSH Browser

MeSH Heading: Ancrod
Tree Number(s): D08.811.277.656.300.760.955.060; D08.811.277.656.959.350.955.060; D20.888.850.960.200.050; D23.946.833.850.960.200.050
Unique ID: D000721
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000721
Scope Note: An enzyme fraction from the venom of the Malayan pit viper, Agkistrodon rhodostoma. It catalyzes the hydrolysis of a number of amino acid esters and a limited proteolysis of fibrinogen. It is used clinically to produce controlled defibrination in patients requiring anticoagulant therapy. EC 3.4.21.-.
Entry Term(s): Agkistrodon Serine Proteinase; Agkistrodon rhodostoma Venom Protease; Arvin; Arvin IRC-50; Arwin; Venacil
Pharm Action: Anticoagulants
Fibrinolytic Agents
Registry Numbers: EC 3.4.21.-; 0
Related Numbers: 9046-56-4
Previous Indexing: Peptide Hydrolases (1972-1974); Peptide Peptidohydrolases (1966-1974); Venoms (1972-1974)
Public MeSH Note: 78; was ARVIN see under PEPTIDE PEPTIDOHYDROLASES 1975-77; ARVIN was see ANCROD 1978-95
Online Note: use ANCROD to search ARVIN 1975-77
History Note: 78; was ARVIN see under ENDOPEPTIDASES 1975-77; ARVIN was see ANCROD 1978-95
Date Established: 1978/01/01
Date of Entry: 1974/11/11
Revision Date: 2016/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0001092
Registry Numbers: EC 3.4.21.-
Related Numbers: 9046-56-4
Scope Note: An enzyme fraction from the venom of the Malayan pit viper, Agkistrodon rhodostoma. It catalyzes the hydrolysis of a number of amino acid esters and a limited proteolysis of fibrinogen. It is used clinically to produce controlled defibrination in patients requiring anticoagulant therapy. EC 3.4.21.-.
Terms: Ancrod Preferred Term
Term UI T002165
Date01/01/1999
LexicalTag NON
ThesaurusID; Agkistrodon rhodostoma Venom Protease
Term UI T002166
Date03/20/1990
LexicalTag NON
ThesaurusID NLM (1991); Agkistrodon Serine Proteinase
Term UI T002167
Date03/20/1990
LexicalTag NON
ThesaurusID NLM (1991)

Ancrod MeSH Descriptor Data 2024