note category; an inflamm skin reaction to antibody excess
Scope Note
A dermal inflammatory reaction produced under conditions of antibody excess, when a second injection of antigen produces intravascular antigen-antibody complexes which bind complement, causing cell clumping, endothelial damage, and vascular necrosis.
Entry Term(s)
Arthus Phenomenon
Public MeSH Note
93; was ARTHUS PHENOMENON 1966-92
Online Note
use ARTHUS REACTION to search ARTHUS PHENOMENON 1966-92
A dermal inflammatory reaction produced under conditions of antibody excess, when a second injection of antigen produces intravascular antigen-antibody complexes which bind complement, causing cell clumping, endothelial damage, and vascular necrosis.