MeSH Browser

MeSH Heading: Biopterins
Tree Number(s): D03.633.100.733.631.202; D08.211.090
Unique ID: D001708
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D001708
Annotation: /defic /‌physiol permitted
Scope Note: Pterin derivatives based on 2-amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone. Biopterins are natural products that have been considered as growth factors for some insects. Biopterins are cofactors for the AROMATIC AMINO ACID hydroxylases and NITRIC OXIDE SYNTHASE. Deficiencies in BIOPTERINS metabolism (e.g., lowered TETRAHYDROBIOPTERIN) are associated with neurological deterioration (e.g., HYPERPHENYLALANINAEMIA).
Entry Term(s): 2-Amino-6-((1S,2R)-1,2-dihydroxypropyl)-4(1H)-pteridinone; 2-Amino-6-((1S,2S)-1,2-dihydroxypropyl)-4(1H)-pteridinone; 2-Amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone; 2-Amino-6-(1,2-dihydroxypropyl)-4(8H)-pteridinone; 2-amino-6-((1R,2R)-1,2-dihydroxypropyl)-4(3H)-pteridinone; 4(1H)-Pteridinone, 2-amino-6-(1,2-dihydroxypropyl)-, (S-(R*,S*))-; 6-Biopterin; Biopterin; D-threo-Biopterin; Dictyopterin; L-Biopterin; L-erythro-Biopterin; L-threo-Biopterin; Orinapterin
Related Numbers: 22150-76-1
NLM Classification #: QU 135
Previous Indexing: Propanediols (1972-1974); Pteridines (1970-1974)
Public MeSH Note: 2024; see BIOPTERIN 1987-2013, PTERIDINES 1975-1986
History Note: 2024(1987); use PTERIDINES 1975-1986
Date Established: 1987/01/01
Date of Entry: 1974/11/19
Revision Date: 2023/07/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0002561
Scope Note: A natural product that has been considered as a growth factor for some insects.
Terms: Biopterin Preferred Term
Term UI T004966
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); 2-Amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone
Term UI T004967
Date11/14/1996
LexicalTag NON
ThesaurusID NLM (1998); 2-Amino-6-((1S,2R)-1,2-dihydroxypropyl)-4(1H)-pteridinone
Term UI T001125233
Date10/06/2022
LexicalTag NON
ThesaurusID NLM (2024); L-erythro-Biopterin
Term UI T001125235
Date10/06/2022
LexicalTag NON
ThesaurusID NLM (2024); L-Biopterin
Term UI T001125236
Date10/06/2022
LexicalTag NON
ThesaurusID NLM (2024); 4(1H)-Pteridinone, 2-amino-6-(1,2-dihydroxypropyl)-, (S-(R*,S*))-
Term UI T001125225
Date10/06/2022
LexicalTag NON
ThesaurusID NLM (2024); 6-Biopterin
Term UI T001125227
Date10/06/2022
LexicalTag NON
ThesaurusID NLM (2024)

Biopterins MeSH Descriptor Data 2025