MeSH Browser

MeSH Heading: Calcitriol
Tree Number(s): D04.210.500.247.222.159.478.387.300; D04.210.500.247.808.146.478.387.300; D04.210.500.812.768.196.478.387.300; D10.570.938.146.478.387.300
Unique ID: D002117
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D002117
Annotation: deficiency: coordinate CALCITRIOL /‌defic (IM) with VITAMIN D DEFICIENCY (IM)
Scope Note: The physiologically active form of vitamin D. It is formed primarily in the kidney by enzymatic hydroxylation of 25-hydroxycholecalciferol (CALCIFEDIOL). Its production is stimulated by low blood calcium levels and parathyroid hormone. Calcitriol increases intestinal absorption of calcium and phosphorus, and in concert with parathyroid hormone increases bone resorption.
Entry Term(s): 1 alpha, 25-dihydroxy-20-epi-Vitamin D3; 1 alpha,25-Dihydroxycholecalciferol; 1 alpha,25-Dihydroxyvitamin D3; 1, 25-(OH)2D3; 1,25(OH)2-20epi-D3; 1,25(OH)2D3; 1,25-Dihydroxycholecalciferol; 1,25-Dihydroxyvitamin D3; 1,25-dihydroxy-20-epi-Vitamin D3; 20-epi-1alpha,25-dihydroxycholecaliferol; Bocatriol; Calcijex; Calcitriol KyraMed; Calcitriol-Nefro; Decostriol; MC-1288; MC1288; Osteotriol; Renatriol; Rocaltrol; Silkis; Sitriol; Soltriol; Tirocal
Pharm Action: Calcium Channel Agonists
Vitamins
Bone Density Conservation Agents
Calcium-Regulating Hormones and Agents
Related Numbers: 32222-06-3
CAS Type 1 Name: 9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol, (1alpha,3beta,5Z,7E)-
Previous Indexing: Cholecalciferols (1966-1972); Dihydroxycholecalciferols (1973-1981); Hydroxycholecalciferols (1972-1973)
See Also: Receptors, Calcitriol
Public MeSH Note: 82
History Note: 82
Date Established: 1982/01/01
Date of Entry: 1981/05/12
Revision Date: 2022/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Polycyclic Compounds [D04]
- Fused-Ring Compounds [D04.210]
  - Steroids [D04.210.500]
    - Cholestanes [D04.210.500.247]
      - Cholestenes [D04.210.500.247.222]
        
        Cholecalciferol [D04.210.500.247.222.159]
        
        Hydroxycholecalciferols [D04.210.500.247.222.159.478]
        
        Dihydroxycholecalciferols [D04.210.500.247.222.159.478.387]
        
        Calcitriol [D04.210.500.247.222.159.478.387.300]
        
        24,25-Dihydroxyvitamin D 3 [D04.210.500.247.222.159.478.387.400]

Polycyclic Compounds [D04]
- Fused-Ring Compounds [D04.210]
  - Steroids [D04.210.500]
    - Cholestanes [D04.210.500.247]
      - Sterols [D04.210.500.247.808]
        
        Cholecalciferol [D04.210.500.247.808.146]
        
        Hydroxycholecalciferols [D04.210.500.247.808.146.478]
        
        Dihydroxycholecalciferols [D04.210.500.247.808.146.478.387]
        
        Calcitriol [D04.210.500.247.808.146.478.387.300]
        
        24,25-Dihydroxyvitamin D 3 [D04.210.500.247.808.146.478.387.400]

Polycyclic Compounds [D04]
- Fused-Ring Compounds [D04.210]
  - Steroids [D04.210.500]
    - Secosteroids [D04.210.500.812]
      - Vitamin D [D04.210.500.812.768]
        
        Cholecalciferol [D04.210.500.812.768.196]
        
        Hydroxycholecalciferols [D04.210.500.812.768.196.478]
        
        Dihydroxycholecalciferols [D04.210.500.812.768.196.478.387]
        
        Calcitriol [D04.210.500.812.768.196.478.387.300]
        
        24,25-Dihydroxyvitamin D 3 [D04.210.500.812.768.196.478.387.400]

Lipids [D10]
- Membrane Lipids [D10.570]
  - Sterols [D10.570.938]
    - Cholecalciferol [D10.570.938.146]
      - Hydroxycholecalciferols [D10.570.938.146.478]
        
        Dihydroxycholecalciferols [D10.570.938.146.478.387]
        
        Calcitriol [D10.570.938.146.478.387.300]
        
        24,25-Dihydroxyvitamin D 3 [D10.570.938.146.478.387.400]

Calcitriol Preferred

Concept UI: M0003148
Related Numbers: 32222-06-3
Scope Note: The physiologically active form of vitamin D. It is formed primarily in the kidney by enzymatic hydroxylation of 25-hydroxycholecalciferol (CALCIFEDIOL). Its production is stimulated by low blood calcium levels and parathyroid hormone. Calcitriol increases intestinal absorption of calcium and phosphorus, and in concert with parathyroid hormone increases bone resorption.
Terms: Calcitriol Preferred Term
Term UI T006014
Date01/01/1999
LexicalTag NON
ThesaurusID; 1,25(OH)2D3
Term UI T001119591
Date04/04/2022
LexicalTag NON
ThesaurusID NLM (2023); 1 alpha,25-Dihydroxycholecalciferol
Term UI T006010
Date05/12/1981
LexicalTag NON
ThesaurusID UNK (19XX); 1 alpha,25-Dihydroxyvitamin D3
Term UI T006011
Date05/12/1981
LexicalTag NON
ThesaurusID UNK (19XX); 1,25-Dihydroxycholecalciferol
Term UI T006012
Date05/12/1981
LexicalTag NON
ThesaurusID UNK (19XX); 1,25-Dihydroxyvitamin D3
Term UI T006013
Date05/12/1981
LexicalTag NON
ThesaurusID; 1, 25-(OH)2D3
Term UI T001103320
Date03/24/2021
LexicalTag NON
ThesaurusID NLM (2022)

MC1288 Narrower

20-epi-1alpha,25-dihydroxycholecaliferol Related

Rocaltrol Narrower

Soltriol Narrower

Bocatriol Narrower

Calcijex Narrower

Tirocal Narrower

Sitriol Narrower

Silkis Narrower

Renatriol Narrower

Osteotriol Narrower

Decostriol Narrower

Calcitriol-Nefro Narrower

Calcitriol KyraMed Narrower

Calcitriol MeSH Descriptor Data 2025