NLM Logo

Cantharidin MeSH Descriptor Data 2025


MeSH Heading
Cantharidin
Tree Number(s)
D03.633.100.127.125
Unique ID
D002193
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D002193
Scope Note
A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
Entry Term(s)
Cantharides
Cantharidine
Pharm Action
Enzyme Inhibitors
Irritants
Related Numbers
56-25-7
CAS Type 1 Name
4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aalpha,4beta,7beta,7aalpha)-
Public MeSH Note
79; was CANTHARIDES 1963-78
Online Note
use CANTHARIDIN to search CANTHARIDES 1966-78
History Note
79; was CANTHARIDES 1963-78
Date Established
1979/01/01
Date of Entry
1999/01/01
Revision Date
2016/05/27
Cantharidin Preferred
Cantharides Related
page delivered in 0.151s