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Capillary Permeability MeSH Descriptor Data 2023

MeSH Heading
Capillary Permeability
Tree Number(s)
Unique ID
RDF Unique Identifier
coord IM with endogenous substance /‌metab (IM) or exogenous substance /‌pharmacokin (IM)
Scope Note
The property of blood capillary ENDOTHELIUM that allows for the selective exchange of substances between the blood and surrounding tissues and through membranous barriers such as the BLOOD-AIR BARRIER; BLOOD-AQUEOUS BARRIER; BLOOD-BRAIN BARRIER; BLOOD-NERVE BARRIER; BLOOD-RETINAL BARRIER; and BLOOD-TESTIS BARRIER. Small lipid-soluble molecules such as carbon dioxide and oxygen move freely by diffusion. Water and water-soluble molecules cannot pass through the endothelial walls and are dependent on microscopic pores. These pores show narrow areas (TIGHT JUNCTIONS) which may limit large molecule movement.
Entry Term(s)
Microvascular Permeability
Permeability, Capillary
Permeability, Microvascular
Vascular Permeability
NLM Classification #
WG 700
See Also
Blood-Air Barrier
Blood-Aqueous Barrier
Blood-Brain Barrier
Blood-Nerve Barrier
Blood-Retinal Barrier
Blood-Testis Barrier
Capillary Leak Syndrome
Transendothelial and Transepithelial Migration
Date Established
Date of Entry
Revision Date
Capillary Permeability Preferred
Permeability, Microvascular Broader
Vascular Permeability Broader
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