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Charcot-Marie-Tooth Disease MeSH Descriptor Data 2023


MeSH Heading
Charcot-Marie-Tooth Disease
Tree Number(s)
C10.500.300.200
C10.574.500.495.200
C10.668.829.800.300.200
C16.131.666.300.200
C16.320.400.375.200
Unique ID
D002607
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D002607
Scope Note
A hereditary motor and sensory neuropathy transmitted most often as an autosomal dominant trait and characterized by progressive distal wasting and loss of reflexes in the muscles of the legs (and occasionally involving the arms). Onset is usually in the second to fourth decade of life. This condition has been divided into two subtypes, hereditary motor and sensory neuropathy (HMSN) types I and II. HMSN I is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in HMSN II. (Adams et al., Principles of Neurology, 6th ed, p1343)
Entry Version
CHARCOT MARIE TOOTH DIS
Entry Term(s)
Atrophy, Muscular, Peroneal
Charcot-Marie Disease
Charcot-Marie-Tooth Disease, Autosomal Dominant, With Focally Folded Myelin Sheaths, Type 1A
Charcot-Marie-Tooth Disease, Autosomal Dominant, with Focally Folded Myelin Sheaths, Type 1B
Charcot-Marie-Tooth Disease, Demyelinating, Type 1A
Charcot-Marie-Tooth Disease, Demyelinating, Type 1B
Charcot-Marie-Tooth Disease, Slow Nerve Conduction Type, Linked To Duffy
Charcot-Marie-Tooth Disease, Type 1A
Charcot-Marie-Tooth Disease, Type 1B
Charcot-Marie-Tooth Disease, Type I
Charcot-Marie-Tooth Disease, Type IA
Charcot-Marie-Tooth Disease, Type IB
Charcot-Marie-Tooth Disease, Type II
Charcot-Marie-Tooth Hereditary Neuropathy
Charcot-Marie-Tooth Neuropathy, Type 1A
Charcot-Marie-Tooth Neuropathy, Type 1B
Charcot-Marie-Tooth Syndrome
HMN Distal Type I
HMSN 1A
HMSN 1B
HMSN I
HMSN IA
HMSN IB
HMSN II
HMSN Type I
HMSN Type II
HMSN1A
HMSN1B
Hereditary Areflexic Dystasia
Hereditary Motor And Sensory Neuropathy IB
Hereditary Motor and Sensory Neuropathy 1A
Hereditary Motor and Sensory Neuropathy 1B
Hereditary Motor and Sensory Neuropathy IA
Hereditary Motor and Sensory-Neuropathy Type II
Hereditary Motor, and Sensory Neuropathy Type I
Hereditary Type I Motor and Sensory Neuropathy
Muscular Atrophy, Peroneal
Neuropathy, Type I Hereditary Motor and Sensory
Neuropathy, Type II Hereditary Motor and Sensory
Peroneal Muscular Atrophy
Roussy Levy Hereditary Areflexic Dystasia
Roussy-Levy Disease
Roussy-Levy Hereditary Areflexic Dystasia
Roussy-Levy Syndrome
NLM Classification #
WE 550
See Also
Myelin P0 Protein
Public MeSH Note
2000; see CHARCOT-MARIE DISEASE 1991-1999, see MUSCULAR ATROPHY, SPINAL 1988-1990, see MUSCULAR ATROPHY 1966-1987; for CHARCOT-MARIE-TOOTH DISEASE see CHARCOT-MARIE DISEASE 1991-1999
History Note
2000(1966)
Date Established
1991/01/01
Date of Entry
1999/11/08
Revision Date
2013/07/08
Charcot-Marie-Tooth Disease Preferred
Roussy-Levy Syndrome Related
Hereditary Type I Motor and Sensory Neuropathy Narrower
HMSN Type II Narrower
Charcot-Marie-Tooth Disease, Type IA Narrower
Charcot-Marie-Tooth Disease, Type IB Narrower
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