NLM Logo

Cisplatin MeSH Descriptor Data 2023


MeSH Heading
Cisplatin
Tree Number(s)
D01.210.375
D01.625.125
D01.710.100
Unique ID
D002945
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D002945
Scope Note
An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
Entry Term(s)
Biocisplatinum
Dichlorodiammineplatinum
NSC-119875
Platidiam
Platino
Platinol
Platinum Diamminodichloride
cis-Diamminedichloroplatinum
cis-Diamminedichloroplatinum(II)
cis-Dichlorodiammineplatinum(II)
cis-Platinum
Pharm Action
Antineoplastic Agents
Cross-Linking Reagents
Radiation-Sensitizing Agents
Registry Number
Q20Q21Q62J
Related Numbers
15663-27-1
CAS Type 1 Name
Platinum, diamminedichloro-, (SP-4-2)-
NLM Classification #
QV 269
Previous Indexing
Amines (1966-1973)
Ammonium Compounds (1966-1973)
Chlorides (1966-1973)
Platinum (1966-1973)
Public MeSH Note
84; was see under DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1981-83; was PLATINUM DIAMMINODICHLORIDE see under DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1974-80; DIAMMONIUM CHLOROPLATINUM COMPOUNDS was heading 1974-83
Online Note
use CISPLATIN to search PLATINUM DIAMMINODICHLORIDE 1974-80 & DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1974-83
History Note
84(81); was see under DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1981-83; was PLATINUM DIAMMINODICHLORIDE see under DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1974-80; DIAMMONIUM CHLOROPLATINUM COMPOUNDS was heading 1974-83
Date Established
1984/01/01
Date of Entry
1999/01/01
Revision Date
2013/07/08
Cisplatin Preferred
NSC-119875 Narrower
Platino Narrower
Platinol Narrower
Biocisplatinum Narrower
Platidiam Narrower
page delivered in 0.172s