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Cocaine MeSH Descriptor Data 2023


MeSH Heading
Cocaine
Tree Number(s)
D02.145.074.722.388
D03.132.889.354
D03.605.084.500.722.388
D03.605.869.388
Unique ID
D003042
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D003042
Annotation
cocaine derivatives = COCAINE /‌analogs; CRACK COCAINE, COCAINE SMOKING and COCAINE-RELATED DISORDERS are available
Scope Note
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
Entry Term(s)
Cocaine HCl
Cocaine Hydrochloride
Pharm Action
Anesthetics, Local
Vasoconstrictor Agents
Dopamine Uptake Inhibitors
Registry Number
I5Y540LHVR
Related Numbers
50-36-2
53-21-4
XH8T8T6WZH
CAS Type 1 Name
8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))-
Public MeSH Note
COCAINE DERIVATIVES was see under COCAINE 1975-77; was see under TROPANES 1969-74
Online Note
use COCAINE/analogs & derivatives to search COCAINE DERIVATIVES 1975-77; use TROPANES 1969-74
History Note
COCAINE DERIVATIVES was see under COCAINE 1975-77; was see under TROPANES 1969-74
Date Established
1960/01/01
Date of Entry
1999/01/01
Revision Date
2016/05/28
Cocaine Preferred
Cocaine Hydrochloride Narrower
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