MeSH Browser

MeSH Heading: Dextrorphan
Tree Number(s): D03.132.577.249.235; D03.605.497.260; D03.633.400.686.260; D04.615.723.795.235
Unique ID: D003917
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D003917
Scope Note: Dextro form of levorphanol. It acts as a noncompetitive NMDA receptor antagonist, among other effects, and has been proposed as a neuroprotective agent. It is also a metabolite of DEXTROMETHORPHAN.
Entry Term(s): (+-)-17-Methylmorphinan-3-ol
Pharm Action: Excitatory Amino Acid Antagonists
Neuroprotective Agents
Registry Number: 04B7QNO9WS
Related Numbers: 125-73-5
CAS Type 1 Name: Morphinan-3-ol, 17-methyl-, (9alpha,13alpha,14alpha)-
Previous Indexing: Morphinans (1969-1974)
Public MeSH Note: 91; was see under MORPHINANS 1975-90; DEXTRODROMORAN & D-DROMORAN were see DEXTRORPHAN 1977-94; DESTRORPHANOLUM was see DEXTRORPHAN 1975-94
Online Note: use DEXTRORPHAN to search DEXTRODROMORAN & D-DROMORAN 1977-94 & DESTRORPHANOLUM 1975-94
History Note: 91(75); was see under MORPHINANS 1975-90; DEXTRODROMORAN & D-DROMORAN were see DEXTRORPHAN 1977-94; DESTRORPHANOLUM was see DEXTRORPHAN 1975-94
Date Established: 1991/01/01
Date of Entry: 1974/11/27
Revision Date: 2016/05/29

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Dextrorphan MeSH Descriptor Data 2023