MeSH Browser

MeSH Heading: Dimethylallyltranstransferase
Tree Number(s): D08.811.913.225.400
Unique ID: D004122
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D004122
Scope Note: An enzyme that, in the pathway of cholesterol biosynthesis, catalyzes the condensation of isopentenyl pyrophosphate and dimethylallylpyrophosphate to yield pyrophosphate and geranylpyrophosphate. The enzyme then catalyzes the condensation of the latter compound with another molecule of isopentenyl pyrophosphate to yield pyrophosphate and farnesylpyrophosphate. EC 2.5.1.1.
Entry Term(s): Dimethylallyltransferase; Dolichyl Phosphate Synthetase; Geranylgeranyl Pyrophosphate Synthetase; Geranylpyrophosphate Synthetase; Nerylpyrophosphate Synthetase; Prenyltransferase
Related Numbers: 9032-79-5
CAS Type 1 Name: Dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyl (trans) transferase
Previous Indexing: Allyl Compounds (1971-1978); Transferases (1966-1978)
Public MeSH Note: 97; was DIMETHYLALLYLTRANSFERASE 1979-96 (see under TRANSFERASES 1979-90)
History Note: 97; was DIMETHYLALLYLTRANSFERASE 1979-96 (see under TRANSFERASES 1979-90)
Date Established: 1991/01/01
Date of Entry: 1978/05/18
Revision Date: 2014/06/13

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0006457
Related Numbers: 9032-79-5
Scope Note: An enzyme that, in the pathway of cholesterol biosynthesis, catalyzes the condensation of isopentenyl pyrophosphate and dimethylallylpyrophosphate to yield pyrophosphate and geranylpyrophosphate. The enzyme then catalyzes the condensation of the latter compound with another molecule of isopentenyl pyrophosphate to yield pyrophosphate and farnesylpyrophosphate. EC 2.5.1.1.
Terms: Dimethylallyltranstransferase Preferred Term
Term UI T012534
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1979); Dimethylallyltransferase
Term UI T012527
Date12/13/1995
LexicalTag NON
ThesaurusID NLM (1997); Dolichyl Phosphate Synthetase
Term UI T012528
Date04/27/1981
LexicalTag NON
ThesaurusID UNK (19XX); Geranylpyrophosphate Synthetase
Term UI T012531
Date05/18/1978
LexicalTag NON
ThesaurusID UNK (19XX); Nerylpyrophosphate Synthetase
Term UI T012532
Date02/10/1981
LexicalTag NON
ThesaurusID UNK (19XX); Prenyltransferase
Term UI T012533
Date05/18/1978
LexicalTag NON
ThesaurusID UNK (19XX)

Dimethylallyltranstransferase MeSH Descriptor Data 2025