MeSH Browser

MeSH Heading: Spermine Synthase
Tree Number(s): D08.811.913.225.912
Unique ID: D013097
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D013097
Annotation: do not confuse with SPERMIDINE SYNTHASE
Scope Note: An enzyme that catalyzes the transfer of the propylamine moiety from 5'-deoxy-5'-S-(3-methylthiopropylamine)sulfonium adenosine to spermidine in the biosynthesis of spermine. It has an acidic isoelectric point at pH 5.0. EC 2.5.1.22.
Entry Term(s): Spermidine Aminopropyltransferase; Spermine Synthetase
Related Numbers: 74812-43-4
CAS Type 1 Name: S-Adenosylmethioninamine:spermidine 3-aminopropyltransferase
Previous Indexing: Propylamines (1972-1974); Spermine (1972-1974); Transferases (1972-1974)
Public MeSH Note: 91; was see under TRANSFERASES 1975-90
History Note: 91(75); was see under TRANSFERASES 1975-90
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Spermine Synthase MeSH Descriptor Data 2025