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Doxepin MeSH Descriptor Data 2023


MeSH Heading
Doxepin
Tree Number(s)
D02.355.291.852.500
D03.633.300.382.393
Unique ID
D004316
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004316
Scope Note
A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
Entry Term(s)
Apo-Doxepin
Aponal
Deptran
Desidox
Doneurin
Doxepia
Doxepin Hydrochloride
Doxepin Hydrochloride, Cis-Trans Isomer Mixture (approximately 1:5)
Doxepin beta
Doxepin-RPh
Espadox
Mareen
Novo-Doxepin
Prudoxin
Quitaxon
Sinequan
Sinquan
Xepin
Zonalon
Pharm Action
Sleep Aids, Pharmaceutical
Antidepressive Agents, Tricyclic
Histamine Antagonists
Registry Number
1668-19-5
Related Numbers
1229-29-4
5ASJ6HUZ7D
CAS Type 1 Name
1-Propanamine, 3-dibenz(b,e)oxepin-11(6H)-ylidene-N,N-dimethyl-
Public MeSH Note
74
History Note
74
Date Established
1974/01/01
Date of Entry
1999/01/01
Revision Date
2016/05/31
Doxepin Preferred
Deptran Narrower
Desidox Narrower
Doneurin Narrower
Doxepia Narrower
Doxepin beta Narrower
Doxepin Hydrochloride Narrower
Doxepin-RPh Narrower
Espadox Narrower
Mareen Narrower
Novo-Doxepin Narrower
Prudoxin Narrower
Quitaxon Narrower
Sinequan Narrower
Zonalon Narrower
Aponal Narrower
Apo-Doxepin Narrower
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