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Doxepin MeSH Descriptor Data 2024


MeSH Heading
Doxepin
Tree Number(s)
D02.355.291.852.500
D03.633.300.382.393
Unique ID
D004316
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004316
Scope Note
A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
Entry Term(s)
Apo-Doxepin
Aponal
Deptran
Desidox
Doneurin
Doxepia
Doxepin Hydrochloride
Doxepin Hydrochloride, Cis-Trans Isomer Mixture (approximately 1:5)
Doxepin beta
Doxepin-RPh
Espadox
Mareen
Novo-Doxepin
Prudoxin
Quitaxon
Sinequan
Sinquan
Xepin
Zonalon
Pharm Action
Antidepressive Agents, Tricyclic
Histamine Antagonists
Sleep Aids, Pharmaceutical
Registry Numbers
1668-19-5
0
5ASJ6HUZ7D
Related Numbers
1229-29-4
5ASJ6HUZ7D
CAS Type 1 Name
1-Propanamine, 3-dibenz(b,e)oxepin-11(6H)-ylidene-N,N-dimethyl-
Public MeSH Note
74
History Note
74
Date Established
1974/01/01
Date of Entry
1999/01/01
Revision Date
2016/05/31
Doxepin Preferred
Sinequan Narrower
Doxepin Hydrochloride Narrower
Zonalon Narrower
Desidox Narrower
Deptran Narrower
Aponal Narrower
Apo-Doxepin Narrower
Doxepin beta Narrower
Doxepia Narrower
Doneurin Narrower
Quitaxon Narrower
Prudoxin Narrower
Novo-Doxepin Narrower
Mareen Narrower
Espadox Narrower
Doxepin-RPh Narrower
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