MeSH Browser

MeSH Heading: Ethacrynic Acid
Tree Number(s): D02.241.081.018.386.682.300; D02.241.511.316.682.200
Unique ID: D004976
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D004976
Scope Note: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
Entry Term(s): Edecrin; Etacrynic Acid; Ethacrinic Acid; Ethacrynate Sodium; Ethacrynic Acid, Sodium Salt; Hydromedin
Pharm Action: Diuretics
Enzyme Inhibitors
Related Numbers: 58-54-8; 6500-81-8; K41MYV7MPM
CAS Type 1 Name: Acetic acid, (2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy)-
Public MeSH Note: 66
History Note: 66(63)
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0007812
Related Numbers: 58-54-8; 6500-81-8; K41MYV7MPM
Scope Note: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
Terms: Ethacrynic Acid Preferred Term
Term UI T015187
Date01/01/1999
LexicalTag NON
ThesaurusID; Etacrynic Acid
Term UI T015189
Date02/17/1983
LexicalTag NON
ThesaurusID; Ethacrinic Acid
Term UI T015190
Date01/13/1997
LexicalTag NON
ThesaurusID NLM (1998)

Ethacrynic Acid MeSH Descriptor Data 2025