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Fusaric Acid MeSH Descriptor Data 2023


MeSH Heading
Fusaric Acid
Tree Number(s)
D03.066.707.200
D03.383.725.705.200
Unique ID
D005669
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D005669
Annotation
/biosyn permitted if by organism
Scope Note
A picolinic acid derivative isolated from various Fusarium species. It has been proposed for a variety of therapeutic applications but is primarily used as a research tool. Its mechanisms of action are poorly understood. It probably inhibits DOPAMINE BETA-HYDROXYLASE, the enzyme that converts dopamine to norepinephrine. It may also have other actions, including the inhibition of cell proliferation and DNA synthesis.
Entry Term(s)
5-Butyl-2-pyridinedicarboxylic Acid
Calcium Fusarate
Pharm Action
Enzyme Inhibitors
Dopamine Agents
Nucleic Acid Synthesis Inhibitors
Registry Number
JWJ963070N
Related Numbers
536-69-6
CAS Type 1 Name
2-Pyridinecarboxylic acid, 5-butyl-
Previous Indexing
Picolinic Acids (1969-1974)
Public MeSH Note
91; was see under PICOLINIC ACIDS 1975-90
History Note
91(75); was see under PICOLINIC ACIDS 1975-90
Date Established
1991/01/01
Date of Entry
1974/11/19
Revision Date
2016/05/31
Fusaric Acid Preferred
Calcium Fusarate Narrower
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