MeSH Browser

MeSH Heading: Galactosylceramidase
Tree Number(s): D08.811.277.450.410.120
Unique ID: D005698
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D005698
Annotation: /defic: consider also LEUKODYSTROPHY, GLOBOID CELL
Scope Note: An enzyme that hydrolyzes galactose from ceramide monohexosides. Deficiency of this enzyme may cause globoid cell leukodystrophy (LEUKODYSTROPHY, GLOBOID CELL). EC 3.2.1.46.
Entry Term(s): Galactocerebrosidase; Galactosylceramide Galactosidase; Galactosylceramide beta-Galactosidase; Galactosylcerebroside beta-Galactosidase
Registry Numbers: EC 3.2.1.46
CAS Type 1 Name: D-Galactosyl-N-acylsphingosine galactohydrolase
Previous Indexing: Cerebrosides (1972-1974); Galactose (1972-1974); Glycoside Hydrolases (1972-1974)
See Also: Leukodystrophy, Globoid Cell
Public MeSH Note: 91; was see under GALACTOSIDASES 1975-90
History Note: 91(75); was see under GALACTOSIDASES 1975-90
Date Introduced: 1991/01/01
Last Updated: 2012/07/03

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0008946
Registry Numbers: EC 3.2.1.46
Scope Note: An enzyme that hydrolyzes galactose from ceramide monohexosides. Deficiency of this enzyme may cause globoid cell leukodystrophy (LEUKODYSTROPHY, GLOBOID CELL). EC 3.2.1.46.
Terms: Galactosylceramidase Preferred Term
Term UI T017219
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); Galactocerebrosidase
Term UI T017218
Date11/11/1974
LexicalTag NON
ThesaurusID UNK (19XX); Galactosylceramide beta-Galactosidase
Term UI T017220
Date01/08/1981
LexicalTag NON
ThesaurusID UNK (19XX); Galactosylceramide Galactosidase
Term UI T017221
Date02/23/1983
LexicalTag NON
ThesaurusID UNK (19XX); Galactosylcerebroside beta-Galactosidase
Term UI T017222
Date02/04/1982
LexicalTag NON
ThesaurusID UNK (19XX)

Galactosylceramidase MeSH Descriptor Data 2026