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Glutamate-Cysteine Ligase MeSH Descriptor Data 2022


MeSH Heading
Glutamate-Cysteine Ligase
Tree Number(s)
D08.811.464.259.850.400
Unique ID
D005721
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D005721
Scope Note
One of the enzymes active in the gamma-glutamyl cycle. It catalyzes the synthesis of gamma-glutamylcysteine from glutamate and cysteine in the presence of ATP with the formation of ADP and orthophosphate. EC 6.3.2.2.
Entry Term(s)
Glutamylcysteine Synthetase
gamma-Glutamyl-Cysteine Synthetase
Registry Number
EC 6.3.2.2
Related Numbers
9023-64-7
CAS Type 1 Name
L-Glutamate:L-cysteine gamma-ligase (ADP-forming)
Previous Indexing
Cysteine (1973-1976)
Glutamates (1973-1976)
Peptide Synthetases (1973-1976)
Public MeSH Note
98; see GAMMA-GLUTAMYL-CYSTEINE SYNTHETASE 1991-97; see PEPTIDE SYNTHETASES 1977-90
History Note
98(77)
Date Established
1991/01/01
Date of Entry
1976/05/19
Revision Date
2003/07/09
Glutamate-Cysteine Ligase Preferred
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