MeSH Browser

MeSH Heading: Glutathione Synthase
Tree Number(s): D08.811.464.259.850.500
Unique ID: D005981
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D005981
Scope Note: One of the enzymes active in the gamma-glutamyl cycle. It catalyzes the synthesis of glutathione from gamma-glutamylcysteine and glycine in the presence of ATP with the formation of ADP and orthophosphate. EC 6.3.2.3.
Entry Term(s): Glutathione Synthetase
Related Numbers: 9023-62-5
CAS Type 1 Name: gamma-L-Glutamyl-L-cysteine:glycine ligase (ADP-forming)
Previous Indexing: Glutathione (1973-1976); Peptide Synthetases (1973-1976)
Public MeSH Note: 98; see GLUTATHIONE SYNTHETASE 1991-97; see PEPTIDE SYNTHETASES 1977-90
History Note: 98(77)
Date Established: 1991/01/01
Date of Entry: 1976/05/19
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Glutathione Synthase MeSH Descriptor Data 2025