MeSH Browser

MeSH Heading: Guanosine Tetraphosphate
Tree Number(s): D03.633.100.759.646.454.480; D13.695.667.454.480; D13.695.827.426.480
Unique ID: D006159
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D006159
Scope Note: Guanosine 5'-diphosphate 2'(3')-diphosphate. A guanine nucleotide containing four phosphate groups. Two phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids are not available for protein synthesis. Synonym: magic spot I.
Entry Term(s): Alarmone ppGpp; Bacterial Magic Spot ppGpp; Guanosine 3'-Diphosphate 5'-Diphosphate; Guanosine 5'-(trihydrogen diphosphate), mono(trihydrogen diphosphate) (ester); Guanosine 5'-Diphosphate 3'-Diphosphate; Guanosine 5'-diphosphate 2'(3')-diphosphate; ppGpp
Registry Number: 33503-72-9
Previous Indexing: Guanine Nucleotides (1966-1977)
Public MeSH Note: 91; was see under GUANINE NUCLEOTIDES 1978-90
History Note: 91(78); was see under GUANINE NUCLEOTIDES 1978-90
Date Established: 1991/01/01
Date of Entry: 1977/04/22
Revision Date: 2020/02/28

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0009693
Registry Number: 33503-72-9
Scope Note: Guanosine 5'-diphosphate 2'(3')-diphosphate. A guanine nucleotide containing four phosphate groups. Two phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids are not available for protein synthesis. Synonym: magic spot I.
Terms: Guanosine Tetraphosphate Preferred Term
Term UI T018691
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1978); ppGpp
Term UI T001006147
Date01/24/2020
LexicalTag NON
ThesaurusID NLM (2021); Bacterial Magic Spot ppGpp
Term UI T001006148
Date01/24/2020
LexicalTag NON
ThesaurusID NLM (2021); Guanosine 5'-Diphosphate 3'-Diphosphate
Term UI T018690
Date09/15/1983
LexicalTag NON
ThesaurusID UNK (19XX); Alarmone ppGpp
Term UI T001006150
Date01/24/2020
LexicalTag NON
ThesaurusID NLM (2021); Guanosine 3'-Diphosphate 5'-Diphosphate
Term UI T018689
Date05/19/1982
LexicalTag NON
ThesaurusID UNK (19XX); Guanosine 5'-(trihydrogen diphosphate), mono(trihydrogen diphosphate) (ester)
Term UI T001006146
Date01/24/2020
LexicalTag NON
ThesaurusID NLM (2021); Guanosine 5'-diphosphate 2'(3')-diphosphate
Term UI T001006149
Date01/24/2020
LexicalTag NON
ThesaurusID NLM (2021)

Guanosine Tetraphosphate MeSH Descriptor Data 2023