MeSH Browser

MeSH Heading: Hypoaldosteronism
Tree Number(s): C19.053.500.480
Unique ID: D006994
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D006994
Annotation: do not confuse with HYPERALDOSTERONISM or PSEUDOHYPOALDOSTERONISM
Scope Note: A congenital or acquired condition of insufficient production of ALDOSTERONE by the ADRENAL CORTEX leading to diminished aldosterone-mediated synthesis of Na(+)-K(+)-EXCHANGING ATPASE in renal tubular cells. Clinical symptoms include HYPERKALEMIA, sodium-wasting, HYPOTENSION, and sometimes metabolic ACIDOSIS.
Entry Term(s): Acidosis, Renal Tubular Type IV; Hypoaldosteronism, Hyporeninemic; Hyporeninemic Hypoaldosteronism; Renal Tubular Acidosis, Type IV; Type IV Renal Tubular Acidosis
Previous Indexing: Adrenal Gland Hypofunction (1966-1987); Aldosterone (1966-1987)
Public MeSH Note: 88
History Note: 88
Date Established: 1988/01/01
Date of Entry: 1987/03/13
Revision Date: 2006/07/05

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0010888
Scope Note: A selective aldosterone deficiency resulting from diminished RENIN-generated ANGIOTENSIN II, a key stimulus to aldosterone secretion. Previously, it was called type IV renal tubular acidosis.
Terms: Hypoaldosteronism, Hyporeninemic Preferred Term
Term UI T020976
Date03/13/1987
LexicalTag NON
ThesaurusID UNK (19XX); Acidosis, Renal Tubular Type IV
Term UI T020977
Date06/16/1997
LexicalTag NON
ThesaurusID NLM (1998); Hyporeninemic Hypoaldosteronism
Term UI T657488
Date11/01/2005
LexicalTag NON
ThesaurusID NLM (2007); Renal Tubular Acidosis, Type IV
Term UI T020979
Date06/16/1997
LexicalTag NON
ThesaurusID NLM (1998); Type IV Renal Tubular Acidosis
Term UI T020978
Date06/16/1997
LexicalTag NON
ThesaurusID NLM (1998)

Hypoaldosteronism MeSH Descriptor Data 2025