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Addison Disease MeSH Descriptor Data 2021


MeSH Heading
Addison Disease
Tree Number(s)
C19.053.500.263
C20.111.163
Unique ID
D000224
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000224
Scope Note
An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.
Entry Version
ADDISON DIS
Entry Term(s)
Addison's Disease
Primary Adrenal Insufficiency
Primary Adrenocortical Insufficiency
Primary Hypoadrenalism
NLM Classification #
WK 765
Public MeSH Note
2005; see ADDISON'S DISEASE 1966-2004
History Note
2005 (1963)
Date Established
1960/01/01
Date of Entry
1999/01/01
Revision Date
2012/07/03
Addison Disease Preferred
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