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Immunoglobulin G4-Related Disease MeSH Descriptor Data 2025


MeSH Heading
Immunoglobulin G4-Related Disease
Tree Number(s)
C20.111.572
Unique ID
D000077733
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077733
Scope Note
A spectrum of systemic autoimmune diseases in which IMMUNOGLOBULIN G4 plays a pathophysiologic role. It can affect multiple organs in highly variable presentations, characterized by inflammatory lesions composed of IgG4-positive PLASMA CELLS, further infiltrated by T helper cells (T-LYMPHOCYTES, HELPER-INDUCER) when linked to progressive FIBROSIS and eventual organ damage.
Entry Term(s)
IgG4 Related Systemic Disease
IgG4-Associated Autoimmune Disease
IgG4-RD
IgG4-Related Disease
IgG4-Related Kidney Disease
IgG4-Related Sclerosing Disease
Immunoglobulin G4-Related Kidney Disease
Immunoglobulin G4-Related Sclerosing Disease
Previous Indexing
Autoimmune Diseases (2010-2018)
Immunoglobulin G (2009-2018)
Public MeSH Note
2019
History Note
2019
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2020/01/16
Immunoglobulin G4-Related Disease Preferred
IgG4-Related Kidney Disease Related
IgG4-Related Sclerosing Disease Narrower
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