MeSH Browser

MeSH Heading: T-Lymphocytes, Helper-Inducer
Tree Number(s): A11.118.637.555.567.550.500.400; A11.118.637.555.567.569.200.400; A11.118.637.555.567.569.500.400; A15.145.229.637.555.567.550.500.400; A15.145.229.637.555.567.569.200.400; A15.145.229.637.555.567.569.500.400; A15.382.490.555.567.550.500.400; A15.382.490.555.567.569.200.400; A15.382.490.555.567.569.500.400
Unique ID: D006377
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D006377
Annotation: subpopulations: coordinate IM with T-LYMPHOCYTE SUBSETS (IM)
Scope Note: Subpopulation of CD4+ lymphocytes that cooperate with other lymphocytes (either T or B) to initiate a variety of immune functions. For example, helper-inducer T-cells cooperate with B-cells to produce antibodies to thymus-dependent antigens and with other subpopulations of T-cells to initiate a variety of cell-mediated immune functions.
Entry Term(s): Helper Cell; Helper Cells; Helper T Cell; Helper T-Cells; Helper-Inducer T-Lymphocytes; Inducer Cell; Inducer Cells; T-Cells, Helper-Inducer; T-Lymphocytes, Helper; T-Lymphocytes, Inducer
Previous Indexing: Antibody Formation (1972-1973); T-Lymphocytes (1973-1982)
See Also: Interleukin-2; Lymphocyte Cooperation
Public MeSH Note: 93; was HELPER CELLS 1983-92; was see T-LYMPHOCYTES 1979-82; was see LYMPHOCYTE COOPERATION 1978
Online Note: use T-LYMPHOCYTES, HELPER-INDUCER to search HELPER CELLS 1983-92; use T-LYMPHOCYTES 1979-82 & LYMPHOCYTE COOPERATION 1978
History Note: 93; was HELPER CELLS 1983-92; was see T-LYMPHOCYTES 1979-82; was see LYMPHOCYTE COOPERATION 1978
Date Established: 1983/01/01
Date of Entry: 1982/04/29
Revision Date: 2020/05/27

Allowable Qualifiers: chemistry (CH)

classification (CL)

cytology (CY)

drug effects (DE)

enzymology (EN)

immunology (IM)

metabolism (ME)

microbiology (MI)

parasitology (PS)

pathology (PA)

physiology (PH)

radiation effects (RE)

transplantation (TR)

ultrastructure (UL)

virology (VI)

Cells [A11]
- Blood Cells [A11.118]
  - Leukocytes [A11.118.637]
    - Leukocytes, Mononuclear [A11.118.637.555]
      - Lymphocytes [A11.118.637.555.567]
        
        Lymphocyte Subsets [A11.118.637.555.567.550]
        
        T-Lymphocyte Subsets [A11.118.637.555.567.550.500]
        
        Intraepithelial Lymphocytes [A11.118.637.555.567.550.500.050]
        
        Mucosal-Associated Invariant T Cells [A11.118.637.555.567.550.500.100]
        
        T-Lymphocytes, Cytotoxic [A11.118.637.555.567.550.500.200]
        
        T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.550.500.400]
        
        T Follicular Helper Cells [A11.118.637.555.567.550.500.400.450]
        
        Th1 Cells [A11.118.637.555.567.550.500.400.900]
        
        Th2 Cells [A11.118.637.555.567.550.500.400.905]
        
        Th17 Cells [A11.118.637.555.567.550.500.400.915]
        
        T-Lymphocytes, Regulatory [A11.118.637.555.567.550.500.700]

Cells [A11]
- Blood Cells [A11.118]
  - Leukocytes [A11.118.637]
    - Leukocytes, Mononuclear [A11.118.637.555]
      - Lymphocytes [A11.118.637.555.567]
        
        T-Lymphocytes [A11.118.637.555.567.569]
        
        CD4-Positive T-Lymphocytes [A11.118.637.555.567.569.200]
        
        T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.200.400]
        
        T Follicular Helper Cells [A11.118.637.555.567.569.200.400.450]
        
        Th1 Cells [A11.118.637.555.567.569.200.400.900]
        
        Th2 Cells [A11.118.637.555.567.569.200.400.905]
        
        Th17 Cells [A11.118.637.555.567.569.200.400.915]
        
        T-Lymphocytes, Regulatory [A11.118.637.555.567.569.200.700]

Cells [A11]
- Blood Cells [A11.118]
  - Leukocytes [A11.118.637]
    - Leukocytes, Mononuclear [A11.118.637.555]
      - Lymphocytes [A11.118.637.555.567]
        
        T-Lymphocytes [A11.118.637.555.567.569]
        
        T-Lymphocyte Subsets [A11.118.637.555.567.569.500]
        
        Intraepithelial Lymphocytes [A11.118.637.555.567.569.500.050]
        
        Memory T Cells [A11.118.637.555.567.569.500.075]
        
        Mucosal-Associated Invariant T Cells [A11.118.637.555.567.569.500.100]
        
        T-Lymphocytes, Cytotoxic [A11.118.637.555.567.569.500.200]
        
        T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.500.400]
        
        T Follicular Helper Cells [A11.118.637.555.567.569.500.400.450]
        
        Th1 Cells [A11.118.637.555.567.569.500.400.900]
        
        Th2 Cells [A11.118.637.555.567.569.500.400.905]
        
        Th17 Cells [A11.118.637.555.567.569.500.400.915]
        
        T-Lymphocytes, Regulatory [A11.118.637.555.567.569.500.700]

Hemic and Immune Systems [A15]
- Blood [A15.145]
  - Blood Cells [A15.145.229]
    - Leukocytes [A15.145.229.637]
      - Leukocytes, Mononuclear [A15.145.229.637.555]
        
        Lymphocytes [A15.145.229.637.555.567]
        
        Lymphocyte Subsets [A15.145.229.637.555.567.550]
        
        T-Lymphocyte Subsets [A15.145.229.637.555.567.550.500]
        
        Intraepithelial Lymphocytes [A15.145.229.637.555.567.550.500.050]
        
        Memory T Cells [A15.145.229.637.555.567.550.500.075]
        
        Mucosal-Associated Invariant T Cells [A15.145.229.637.555.567.550.500.100]
        
        T-Lymphocytes, Cytotoxic [A15.145.229.637.555.567.550.500.200]
        
        T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.550.500.400]
        
        T Follicular Helper Cells [A15.145.229.637.555.567.550.500.400.250]
        
        Th1 Cells [A15.145.229.637.555.567.550.500.400.500]
        
        Th2 Cells [A15.145.229.637.555.567.550.500.400.750]
        
        Th17 Cells [A15.145.229.637.555.567.550.500.400.770]
        
        T-Lymphocytes, Regulatory [A15.145.229.637.555.567.550.500.700]

Hemic and Immune Systems [A15]
- Blood [A15.145]
  - Blood Cells [A15.145.229]
    - Leukocytes [A15.145.229.637]
      - Leukocytes, Mononuclear [A15.145.229.637.555]
        
        Lymphocytes [A15.145.229.637.555.567]
        
        T-Lymphocytes [A15.145.229.637.555.567.569]
        
        CD4-Positive T-Lymphocytes [A15.145.229.637.555.567.569.200]
        
        T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.200.400]
        
        T Follicular Helper Cells [A15.145.229.637.555.567.569.200.400.250]
        
        Th1 Cells [A15.145.229.637.555.567.569.200.400.500]
        
        Th2 Cells [A15.145.229.637.555.567.569.200.400.750]
        
        Th17 Cells [A15.145.229.637.555.567.569.200.400.770]
        
        T-Lymphocytes, Regulatory [A15.145.229.637.555.567.569.200.700]

Hemic and Immune Systems [A15]
- Blood [A15.145]
  - Blood Cells [A15.145.229]
    - Leukocytes [A15.145.229.637]
      - Leukocytes, Mononuclear [A15.145.229.637.555]
        
        Lymphocytes [A15.145.229.637.555.567]
        
        T-Lymphocytes [A15.145.229.637.555.567.569]
        
        T-Lymphocyte Subsets [A15.145.229.637.555.567.569.500]
        
        Intraepithelial Lymphocytes [A15.145.229.637.555.567.569.500.050]
        
        Memory T Cells [A15.145.229.637.555.567.569.500.075]
        
        Mucosal-Associated Invariant T Cells [A15.145.229.637.555.567.569.500.100]
        
        T-Lymphocytes, Cytotoxic [A15.145.229.637.555.567.569.500.200]
        
        T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.500.400]
        
        Th1 Cells [A15.145.229.637.555.567.569.500.400.500]
        
        Th2 Cells [A15.145.229.637.555.567.569.500.400.750]
        
        Th17 Cells [A15.145.229.637.555.567.569.500.400.770]
        
        T-Lymphocytes, Regulatory [A15.145.229.637.555.567.569.500.700]

Hemic and Immune Systems [A15]
- Immune System [A15.382]
  - Leukocytes [A15.382.490]
    - Leukocytes, Mononuclear [A15.382.490.555]
      - Lymphocytes [A15.382.490.555.567]
        
        Lymphocyte Subsets [A15.382.490.555.567.550]
        
        T-Lymphocyte Subsets [A15.382.490.555.567.550.500]
        
        Intraepithelial Lymphocytes [A15.382.490.555.567.550.500.050]
        
        Memory T Cells [A15.382.490.555.567.550.500.075]
        
        Mucosal-Associated Invariant T Cells [A15.382.490.555.567.550.500.100]
        
        T-Lymphocytes, Cytotoxic [A15.382.490.555.567.550.500.200]
        
        T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.550.500.400]
        
        T Follicular Helper Cells [A15.382.490.555.567.550.500.400.450]
        
        Th1 Cells [A15.382.490.555.567.550.500.400.900]
        
        Th2 Cells [A15.382.490.555.567.550.500.400.905]
        
        Th17 Cells [A15.382.490.555.567.550.500.400.915]
        
        T-Lymphocytes, Regulatory [A15.382.490.555.567.550.500.700]

Hemic and Immune Systems [A15]
- Immune System [A15.382]
  - Leukocytes [A15.382.490]
    - Leukocytes, Mononuclear [A15.382.490.555]
      - Lymphocytes [A15.382.490.555.567]
        
        T-Lymphocytes [A15.382.490.555.567.569]
        
        CD4-Positive T-Lymphocytes [A15.382.490.555.567.569.200]
        
        T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.200.400]
        
        T Follicular Helper Cells [A15.382.490.555.567.569.200.400.450]
        
        Th1 Cells [A15.382.490.555.567.569.200.400.900]
        
        Th2 Cells [A15.382.490.555.567.569.200.400.905]
        
        Th17 Cells [A15.382.490.555.567.569.200.400.915]
        
        T-Lymphocytes, Regulatory [A15.382.490.555.567.569.200.700]

Hemic and Immune Systems [A15]
- Immune System [A15.382]
  - Leukocytes [A15.382.490]
    - Leukocytes, Mononuclear [A15.382.490.555]
      - Lymphocytes [A15.382.490.555.567]
        
        T-Lymphocytes [A15.382.490.555.567.569]
        
        T-Lymphocyte Subsets [A15.382.490.555.567.569.500]
        
        Intraepithelial Lymphocytes [A15.382.490.555.567.569.500.050]
        
        Memory T Cells [A15.382.490.555.567.569.500.075]
        
        Mucosal-Associated Invariant T Cells [A15.382.490.555.567.569.500.100]
        
        T-Lymphocytes, Cytotoxic [A15.382.490.555.567.569.500.200]
        
        T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.500.400]
        
        T Follicular Helper Cells [A15.382.490.555.567.569.500.400.450]
        
        Th1 Cells [A15.382.490.555.567.569.500.400.900]
        
        Th2 Cells [A15.382.490.555.567.569.500.400.905]
        
        Th17 Cells [A15.382.490.555.567.569.500.400.915]
        
        T-Lymphocytes, Regulatory [A15.382.490.555.567.569.500.700]

T-Lymphocytes, Helper-Inducer Preferred

Concept UI: M0010015
Scope Note: Subpopulation of CD4+ lymphocytes that cooperate with other lymphocytes (either T or B) to initiate a variety of immune functions. For example, helper-inducer T-cells cooperate with B-cells to produce antibodies to thymus-dependent antigens and with other subpopulations of T-cells to initiate a variety of cell-mediated immune functions.
Terms: T-Lymphocytes, Helper-Inducer Preferred Term
Term UI T019302
Date01/01/1999
LexicalTag ABX
ThesaurusID NLM (1983); Helper Cell
Term UI T001010868
Date03/25/2020
LexicalTag NON
ThesaurusID NLM (2021); T-Lymphocytes, Helper
Term UI T019297
Date04/29/1982
LexicalTag NON
ThesaurusID UNK (19XX); T-Lymphocytes, Inducer
Term UI T019298
Date04/17/1984
LexicalTag NON
ThesaurusID UNK (19XX); Helper Cells
Term UI T019295
Date10/04/1991
LexicalTag NON
ThesaurusID NLM (1993); Helper T-Cells
Term UI T019299
Date10/04/1991
LexicalTag NON
ThesaurusID NLM (1993); Helper-Inducer T-Lymphocytes
Term UI T019301
Date10/04/1991
LexicalTag NON
ThesaurusID NLM (1993); Inducer Cells
Term UI T019296
Date04/17/1984
LexicalTag NON
ThesaurusID UNK (19XX); T-Cells, Helper-Inducer
Term UI T019300
Date10/09/1991
LexicalTag NON
ThesaurusID NLM (1993); Helper T Cell
Term UI T001010869
Date03/25/2020
LexicalTag NON
ThesaurusID NLM (2021); Inducer Cell
Term UI T001010870
Date03/25/2020
LexicalTag NON
ThesaurusID NLM (2021)

T-Lymphocytes, Helper-Inducer MeSH Descriptor Data 2025