Mucosal-Associated Invariant T Cells MeSH Descriptor Data 2025

MeSH Heading: Mucosal-Associated Invariant T Cells
Tree Number(s): A11.118.637.555.567.550.500.100; A11.118.637.555.567.569.500.100; A15.145.229.637.555.567.550.500.100; A15.145.229.637.555.567.569.500.100; A15.382.490.555.567.550.500.100; A15.382.490.555.567.569.500.100
Unique ID: D000072336
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000072336
Scope Note: A subset of T-lymphocytes that are present in large numbers at MUCOUS MEMBRANES and respond to INFECTIONS. They express a conserved invariant T-CELL RECEPTOR ALPHA-CHAIN that enables them to respond to infections by sensing RIBOFLAVIN metabolites of pathogens.
Entry Term(s): MAIT Cell; MAIT Cells; Mucosal-Associated Invariant T Cell
Previous Indexing: T-Lymphocytes (2005-2016); T-Lymphocyte Subsets (2003-2016)
Public MeSH Note: 2017
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2020/05/27

Allowable Qualifiers: chemistry (CH)

classification (CL)

cytology (CY)

drug effects (DE)

enzymology (EN)

immunology (IM)

metabolism (ME)

microbiology (MI)

parasitology (PS)

pathology (PA)

physiology (PH)

radiation effects (RE)

transplantation (TR)

ultrastructure (UL)

virology (VI)

Cells [A11]
- Blood Cells [A11.118]
  - Leukocytes [A11.118.637]
    - Leukocytes, Mononuclear [A11.118.637.555]
      - Lymphocytes [A11.118.637.555.567]
        
        Lymphocyte Subsets [A11.118.637.555.567.550]
        
        T-Lymphocyte Subsets [A11.118.637.555.567.550.500]
        
        Intraepithelial Lymphocytes [A11.118.637.555.567.550.500.050]
        
        Mucosal-Associated Invariant T Cells [A11.118.637.555.567.550.500.100]
        
        T-Lymphocytes, Cytotoxic [A11.118.637.555.567.550.500.200]
        
        T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.550.500.400]
        
        T-Lymphocytes, Regulatory [A11.118.637.555.567.550.500.700]

Cells [A11]
- Blood Cells [A11.118]
  - Leukocytes [A11.118.637]
    - Leukocytes, Mononuclear [A11.118.637.555]
      - Lymphocytes [A11.118.637.555.567]
        
        T-Lymphocytes [A11.118.637.555.567.569]
        
        T-Lymphocyte Subsets [A11.118.637.555.567.569.500]
        
        Intraepithelial Lymphocytes [A11.118.637.555.567.569.500.050]
        
        Memory T Cells [A11.118.637.555.567.569.500.075]
        
        Mucosal-Associated Invariant T Cells [A11.118.637.555.567.569.500.100]
        
        T-Lymphocytes, Cytotoxic [A11.118.637.555.567.569.500.200]
        
        T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.500.400]
        
        T-Lymphocytes, Regulatory [A11.118.637.555.567.569.500.700]

Hemic and Immune Systems [A15]
- Blood [A15.145]
  - Blood Cells [A15.145.229]
    - Leukocytes [A15.145.229.637]
      - Leukocytes, Mononuclear [A15.145.229.637.555]
        
        Lymphocytes [A15.145.229.637.555.567]
        
        Lymphocyte Subsets [A15.145.229.637.555.567.550]
        
        T-Lymphocyte Subsets [A15.145.229.637.555.567.550.500]
        
        Intraepithelial Lymphocytes [A15.145.229.637.555.567.550.500.050]
        
        Memory T Cells [A15.145.229.637.555.567.550.500.075]
        
        Mucosal-Associated Invariant T Cells [A15.145.229.637.555.567.550.500.100]
        
        T-Lymphocytes, Cytotoxic [A15.145.229.637.555.567.550.500.200]
        
        T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.550.500.400]
        
        T-Lymphocytes, Regulatory [A15.145.229.637.555.567.550.500.700]

Hemic and Immune Systems [A15]
- Blood [A15.145]
  - Blood Cells [A15.145.229]
    - Leukocytes [A15.145.229.637]
      - Leukocytes, Mononuclear [A15.145.229.637.555]
        
        Lymphocytes [A15.145.229.637.555.567]
        
        T-Lymphocytes [A15.145.229.637.555.567.569]
        
        T-Lymphocyte Subsets [A15.145.229.637.555.567.569.500]
        
        Intraepithelial Lymphocytes [A15.145.229.637.555.567.569.500.050]
        
        Memory T Cells [A15.145.229.637.555.567.569.500.075]
        
        Mucosal-Associated Invariant T Cells [A15.145.229.637.555.567.569.500.100]
        
        T-Lymphocytes, Cytotoxic [A15.145.229.637.555.567.569.500.200]
        
        T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.500.400]
        
        T-Lymphocytes, Regulatory [A15.145.229.637.555.567.569.500.700]

Hemic and Immune Systems [A15]
- Immune System [A15.382]
  - Leukocytes [A15.382.490]
    - Leukocytes, Mononuclear [A15.382.490.555]
      - Lymphocytes [A15.382.490.555.567]
        
        Lymphocyte Subsets [A15.382.490.555.567.550]
        
        T-Lymphocyte Subsets [A15.382.490.555.567.550.500]
        
        Intraepithelial Lymphocytes [A15.382.490.555.567.550.500.050]
        
        Memory T Cells [A15.382.490.555.567.550.500.075]
        
        Mucosal-Associated Invariant T Cells [A15.382.490.555.567.550.500.100]
        
        T-Lymphocytes, Cytotoxic [A15.382.490.555.567.550.500.200]
        
        T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.550.500.400]
        
        T-Lymphocytes, Regulatory [A15.382.490.555.567.550.500.700]

Hemic and Immune Systems [A15]
- Immune System [A15.382]
  - Leukocytes [A15.382.490]
    - Leukocytes, Mononuclear [A15.382.490.555]
      - Lymphocytes [A15.382.490.555.567]
        
        T-Lymphocytes [A15.382.490.555.567.569]
        
        T-Lymphocyte Subsets [A15.382.490.555.567.569.500]
        
        Intraepithelial Lymphocytes [A15.382.490.555.567.569.500.050]
        
        Memory T Cells [A15.382.490.555.567.569.500.075]
        
        Mucosal-Associated Invariant T Cells [A15.382.490.555.567.569.500.100]
        
        T-Lymphocytes, Cytotoxic [A15.382.490.555.567.569.500.200]
        
        T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.500.400]
        
        T-Lymphocytes, Regulatory [A15.382.490.555.567.569.500.700]

Mucosal-Associated Invariant T Cells Preferred

Concept UI: M000616943
Scope Note: A subset of T-lymphocytes that are present in large numbers at MUCOUS MEMBRANES and respond to INFECTIONS. They express a conserved invariant T-CELL RECEPTOR ALPHA-CHAIN that enables them to respond to infections by sensing RIBOFLAVIN metabolites of pathogens.
Terms: Mucosal-Associated Invariant T Cells Preferred Term
Term UI T000899294
Date04/19/2016
LexicalTag NON
ThesaurusID NLM (2017); Mucosal-Associated Invariant T Cell
Term UI T000997844
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); MAIT Cell
Term UI T000997845
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); MAIT Cells
Term UI T000899293
Date04/19/2016
LexicalTag ACX
ThesaurusID NLM (2017)

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