MeSH Browser

MeSH Heading: Ketotifen
Tree Number(s): D02.886.778.370; D03.383.621.370; D03.383.903.370
Unique ID: D007665
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D007665
Scope Note: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
Entry Term(s): 4,9-Dihydro-4-(1-methyl-4-piperidylidene)-10H-benzo(4,5)-cyclohepta(1,2-b)thiophen-10-one; Ketotifen Fumarate; Ketotifene; Ketotiphen; Ketotiphene; Zaditen
Pharm Action: Antipruritics
Histamine H1 Antagonists
Anti-Allergic Agents
Registry Number: X49220T18G
Related Numbers: 34580-13-7; 34580-14-8; HBD503WORO
CAS Type 1 Name: 10H-Benzo(4,5)cyclohepta(1,2-b)thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-
NLM Classification #: QV 157
Previous Indexing: Piperidines (1966-1981); Thiophenes (1966-1981)
Public MeSH Note: 82
History Note: 82
Date Established: 1982/01/01
Date of Entry: 1981/05/13
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0012002
Registry Number: X49220T18G
Related Numbers: 34580-13-7; 34580-14-8; HBD503WORO
Scope Note: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
Terms: Ketotifen Preferred Term
Term UI T023026
Date01/01/1999
LexicalTag NON
ThesaurusID; Ketotiphene
Term UI T023030
Date05/13/1981
LexicalTag NON
ThesaurusID UNK (19XX); Ketotiphen
Term UI T023029
Date05/13/1981
LexicalTag NON
ThesaurusID UNK (19XX); 4,9-Dihydro-4-(1-methyl-4-piperidylidene)-10H-benzo(4,5)-cyclohepta(1,2-b)thiophen-10-one
Term UI T023027
Date03/23/1994
LexicalTag NON
ThesaurusID NLM (1995); Ketotifene
Term UI T023028
Date05/13/1981
LexicalTag NON
ThesaurusID UNK (19XX)

Ketotifen MeSH Descriptor Data 2023