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Crizotinib MeSH Descriptor Data 2021


MeSH Heading
Crizotinib
Tree Number(s)
D03.383.621.154
D03.383.725.050.263
Unique ID
D000077547
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077547
Scope Note
A piperidine and aminopyridine derivative that acts as an inhibitor of RECEPTOR PROTEIN-TYROSINE KINASES, including ANAPLASTIC LYMPHOMA KINASE (ALK) and HEPATOCYTE GROWTH FACTOR RECEPTOR (HGFR; c-Met). It is used in the treatment of NON-SMALL CELL LUNG CANCER.
Entry Term(s)
PF 02341066
PF-02341066
PF-2341066
PF02341066
Xalkori
Pharm Action
Antineoplastic Agents
Protein Kinase Inhibitors
Registry Number
53AH36668S
CAS Type 1 Name
2-Pyridinamine, 3-((1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(4-piperidinyl)-1H-pyrazol-4-yl)-
Public MeSH Note
2010; CRIZOTINIB was indexed under PYRAZOLES and PYRIDINES 2010-2018
History Note
2019 (2010)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/04/09
Crizotinib Preferred
PF-02341066 Narrower
Xalkori Narrower
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