MeSH Browser

MeSH Heading: Neural Tube Defects
Tree Number(s): C10.500.680; C16.131.666.680
Unique ID: D009436
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009436
Annotation: do not confuse entry term SPINAL CORD MYELODYSPLASIA with MYELODYSPLASTIC SYNDROMES, a defect of bone marrow formation
Scope Note: Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)
Entry Term(s): Acrania; Craniorachischisis; Developmental Defects, Neural Tube; Developmental Neural Tube Defects; Diastematomyelia; Exencephaly; Iniencephaly; Neural Tube Developmental Defects; Neurenteric Cyst; Neuroenteric Cyst; Occult Spinal Dysraphism; Occult Spinal Dysraphism Sequence; Spinal Cord Myelodysplasia; Tethered Cord Syndrome; Tethered Spinal Cord Syndrome
Previous Indexing: Anencephaly (1966-1978); Central Nervous System (1966-1978); Spina Bifida (1966-1978)
Public MeSH Note: 1979; for DIASTEMATOMYELIA and TETHERED CORD SYNDROME see SPINA BIFIDA OCCULTA 1991-1999; for NEURENTERIC CYST see SPINA BIFIDA OCCULTA 1991-1999, see NEURAL TUBE DEFECTS 1979-1990
History Note: 1979; for DIASTEMATOMYELIA and TETHERED CORD SYNDROME use SPINA BIFIDA OCCULTA 1991-1999; for NEURENTERIC CYST use SPINA BIFIDA OCCULTA 1991-1999, use NEURAL TUBE DEFECTS 1979-1990
Date Established: 1979/01/01
Date of Entry: 1978/05/15
Revision Date: 2012/07/03

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

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complications (CO)

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urine (UR)

veterinary (VE)

virology (VI)

Nervous System Diseases [C10]
- Nervous System Malformations [C10.500]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Congenital Abnormalities [C16.131]
  - Nervous System Malformations [C16.131.666]

Neural Tube Defects Preferred

Concept UI: M0014686
Scope Note: Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)
Terms: Neural Tube Defects Preferred Term
Term UI T028127
Date01/01/1999
LexicalTag NON
ThesaurusID; Developmental Defects, Neural Tube
Term UI T371778
Date11/08/1999
LexicalTag NON
ThesaurusID NLM (2000); Developmental Neural Tube Defects
Term UI T371779
Date11/08/1999
LexicalTag NON
ThesaurusID NLM (2000); Neural Tube Developmental Defects
Term UI T371780
Date11/08/1999
LexicalTag NON
ThesaurusID NLM (2000)

Diastematomyelia Narrower

Tethered Cord Syndrome Narrower

Craniorachischisis Narrower

Exencephaly Narrower

Spinal Cord Myelodysplasia Narrower

Acrania Narrower

Iniencephaly Narrower

Neurenteric Cyst Narrower

Neural Tube Defects MeSH Descriptor Data 2025